Anti-Apo-E/FITC,熒光素標(biāo)記載脂蛋白E抗體

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產(chǎn)品名稱：Anti-Apo-E/FITC,熒光素標(biāo)記載脂蛋白E抗體  

中文名稱：FITC標(biāo)記的載脂蛋白E抗體

英文名稱：Anti-APOE/FITC 

產(chǎn)品編號：BYK-0167R-FITC 

產(chǎn)品別名：   Apolipoprotein E precursor; AD2; Alzheimer disease 2; Apo E; ApoE; APOEA; ApolipoproteinE; Apolipoprotein-E; Apoprotein; MGC1571; Apo E2; ApoE2; APOE 2; Apolipoprotein E2; LDLCQ5; LPG; APOE_HUMAN; Apo-E. 

本公司另供應(yīng)“FITC標(biāo)記的載脂蛋白D抗體”的其他標(biāo)記有：Alexa Fluor 350     Alexa Fluor 488    Alexa Fluor 555   Alexa Fluor 647    AP    APC    Biotin   Cy3    Cy5    Cy5.5   Cy7    FITC     Gold   HRP   PE   PE-Cy3   PE-CY5   PE-CY5.5   PE-CY7    RBITC.

產(chǎn)品規(guī)格：100ug

產(chǎn)品濃度：  2mg/1ml

亞 型：IgG

純化方法：affinity purified by Protein A

儲 存 液：0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

產(chǎn)品類型：標(biāo)記一抗

抗體來源：Rabbit

克隆類型：polyclonal

保存條件：May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. In vitro, at least isoform 2 and isoform 4 suppress the transforming activity of Abelson murine leukemia virus（v-Abl） after overexpression in fibroblasts. May play a role in regulation EGF-induced Erk pathway activation. Involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 participates in transduction of signals from Ras to Rac. In vitro, a trimeric complex of ABI1, EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor （GEF） activity and ABI1 seems to act as an adapter in the complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA （By similarity）. Recruits WASF1 to lamellipodia and there seems to regulate WASF1 protein level.

Anti-Apo-E/FITC,熒光素標(biāo)記載脂蛋白E抗體   相關(guān)產(chǎn)品：

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Anti-CD133 antigen  造血干細(xì)胞抗原CD133抗體
Anti-CD137/TNFRSF9   CD137抗體
Anti-CD138/Syndecan-1  多配體蛋白聚糖1抗體
Anti-CD146/MCAM  黑色素瘤細(xì)胞粘附分子CD146抗體

  的產(chǎn)品介紹：
Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Compared with E3 and E4, E2 exhibits the lowest receptor binding affinity. Defects in ApoE are a cause of hyperlipoproteinemia type III due to increased plasma cholesterol and triglycerides levels which are the consequence of impaired clearance of chylomicron and VLDL remnants