WAG002 Waglerin-1-FAM (羧基熒光素標(biāo)記Waglerin-1)
- 公司名稱 北京群曉科苑生物技術(shù)有限公司
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- 型號(hào) WAG002
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Waglerin-1-FAM (羧基熒光素標(biāo)記的Waglerin-1)
Waglerin-1 blocks muscle nAChRs
阻斷肌肉乙酰膽堿受體
Waglerin-1 (Wtx-1) is a peptide originally isolated from the venom of the Wagler’s pit viper (Trimeresurus wagleri). This 22 amino-acid peptide is a competitive antagonist of adult muscle nicotinic acetylcholine receptors. Waglerin-1 binds selectively to epsilon subunit of nAChR. Some studies have demonstrated that Waglerin-1 has an effect on ionotropic GABA receptors. It may potentiate or depress I(GABA) depending on the neurons. Some derivatives of Waglerin-1 are currently used in cosmetics to reduce wrinkles. The fluorescent derivative Waglerin-1-FAM can be use to explore the expression and function of the adult nAChR subtypes.
Waglerin-1-FAM技術(shù)資料
氨基酸序列:
FAM-Gly-Gly-Lys-Pro-Asp-Leu-Arg-Pro-Cys9-His-Pro-Pro-Cys13-His-Tyr-Ile-Pro-Arg-Pro-Lys-Pro-Arg-OH
二硫鍵: Cys9-Cys13
長度 (aa): 22
分子式:C133H185N37O32S2
分子量:2878.27 Da
CAS 號(hào):NA
來源:Synthetic
熒光染料:FAM, 5(6)-carboxyfluorescein (λex 492, λem 517)
產(chǎn)品信息
貨號(hào) | 名稱 | 規(guī)格 |
WAG002-00100 | Waglerin-1-FAM (羧基熒光素標(biāo)記的Waglerin-1) | 100ug/500ug/1000ug |
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