CBP73380 KRAS G12C-A59T/BaF3 細胞株
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- 公司名稱 南京科佰生物科技有限公司
- 品牌 cobioer/科佰生物
- 型號 CBP73380
- 產(chǎn)地
- 廠商性質(zhì) 代理商
- 更新時間 2023/6/13 9:25:30
- 訪問次數(shù) 880
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供貨周期 | 現(xiàn)貨 | 規(guī)格 | T-25 Flask |
---|---|---|---|
貨號 | CBP73380 | 應用領(lǐng)域 | 生物產(chǎn)業(yè) |
CBP73380 | |
I. Introduction | |
Cell Line Name: | KRAS G12C-A59T/BaF3 |
Host Cell: | Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS+2ug/ml puromycin |
Mycoplasma Status: | Negative |
II.Background | |
KRAS, KRAS proto-oncogene, GTPase, is a member of the small GTPase superfamily and a key regulator of the MAPK, PI3K/AKT/mTOR pathways (PMID: 23622131). KRAS mutations are identified in a wide range of cancers (PMID: 28666118). | |
III. Representative Data | |
1. Sanger of KRAS G12C-A59T/BaF3 Figure 1. KRAS G12C-A59T/BaF3 G12C Figure 2. KRAS G12C-A59T/BaF3 A59T | |
2. Anti-proliferation assay Figure 3. CTG Proliferation Assay of KRAS G12C/A59T BaF3 Cells (C13). |