Recombinant Human gAcrp30/Adipolean,重組人gAcrp30 / Adipolean

Recombinant Human gAcrp30/Adipolean

產(chǎn)品編號(hào):

450-21

別名:

apm-1,Adipolean （human）

描述:

gAcrp30 is a naturally occurring globular protein, obtained by proteolytic processing of adiponectin. Adiponectin is produced and secreted exclusively by adipocytes, and is a relatively abundant plasma protein, accounting for up to 0.05% of total serum protein. Like Adiponectin, gAcrp30 is capable of decreasing hyperglycemia and reversing insulin resistance. Additionally, gAcrp30 has been shown to be an important factor in promoting fat loss by signaling muscle to absorb and burn Free-Fatty Acids （FFAs）. The signaling receptors for adiponectin and gAcrp30 have recently been identified and names AdipoR1 and AdipoR2. AdipoR2 is predominantly expressed in the liver. Recombinant human gAcrp30/Adipolean is a 16.6 kDa protein consisting of 145 amino acid residues.

氨基酸序列:

MKGEPGEGAY VYRSAFSVGL ETYVTIPNMP IRFTKIFYNNHYDGSTGK FHCNIPGLYY FAYHITVYMK DVKVSLFKKD KAMLFTYDQY QENNVDQASG SVLLHLEVGD QVWLQVYGEG ERNGLYADND NDSTFTGFLL YHDTN

來(lái)源:

E.coli

純度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

Determined by its ability to inhibit the proliferation of murine M1 cells. The expected ED₅₀ for this effect is 1.0-3.0 μg/ml.