目錄:北京索萊寶科技有限公司>>抗體>>Polyclonal Antibody>> K106533PAnti-LAMP1 Polyclonal Antibody
| 參考價(jià) | 面議 |
參考價(jià)：￥ 面議
供貨周期:現(xiàn)貨 規(guī)格:50ul/100ul 貨號(hào):K106533P 應(yīng)用領(lǐng)域:醫(yī)療衛(wèi)生,環(huán)保,化工,生物產(chǎn)業(yè),農(nóng)業(yè) 主要用途:WB IHC
>更新時(shí)間：2022-08-15 05:44:40瀏覽次數(shù)：697評(píng)價(jià)
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| 供貨周期 | 現(xiàn)貨 | 規(guī)格 | 50ul/100ul |
|---|---|---|---|
| 貨號(hào) | K106533P | 應(yīng)用領(lǐng)域 | 醫(yī)療衛(wèi)生,環(huán)保,化工,生物產(chǎn)業(yè),農(nóng)業(yè) |
| 主要用途 | WB IHC |
Anti-LAMP1 Polyclonal Antibody
| 英文名稱(chēng) | Anti-LAMP1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | CD107a;LAMPA;LGP120;lgpA;OTTHUMP00000040663 |
| 應(yīng)用 | WB IHC |
| 稀釋比例 | WB 1:2000-5000.IHC 1:50-200. |
| 交叉反應(yīng) | Human Mouse Rat |
| 蛋白分子量 | 40kDa |
| Gene ID | 3916 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲(chǔ)存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human LAMP1 |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human LAMP1 |
| Subcellular Locations | Cell membrane Endosome membrane Late endosome Lysosome membrane Single-pass type I membrane protein |
| Swiss Prot | P11279 |
| 克隆類(lèi)型 | Polyclonal Antibody |
| 背景資料 | Lysosome associated membrane protein (LAMP1), also known as lgp120 or lgpA, is a type 1 integral membrane protein that is transported from trans Golgi networks to endosomes and then lysosomes. Upon cell activation, LAMP1 transfer to the plasma membrane is dependent on a carboxyl terminal tyrosine based motif (YXXI). Perturbation in the spacing between the tyrosine based motif relative to the membrane abolishes lysosome localization of LAMP1. This mutant protein then cycles between the plasma membrane and the endosome. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation. |
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