目錄:北京索萊寶科技有限公司>>抗體>>Polyclonal Antibody>> K000447PAnti-EIF4G1 Polyclonal Antibody
供貨周期 | 現(xiàn)貨 | 規(guī)格 | 50ul/100ul |
---|---|---|---|
貨號 | K000447P | 應(yīng)用領(lǐng)域 | 醫(yī)療衛(wèi)生,環(huán)保,化工,生物產(chǎn)業(yè),農(nóng)業(yè) |
主要用途 | WB IHC IF |
英文名稱 | Anti-EIF4G1 Polyclonal Antibody |
---|---|
宿主 | Rabbit |
別名 | EIF-4G1;EIF4F;EIF4G;EIF4GI;P220;PARK18 |
應(yīng)用 | WB IHC IF |
稀釋比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
交叉反應(yīng) | Human |
蛋白分子量 | 175kDa |
Gene ID | 1981 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
儲存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
純化方法 | Affinity purification |
亞型 | IgG |
免疫原 | A synthetic peptide of human EIF4G1 |
性狀 | 液體 |
Public Immunogen Range | A synthetic peptide of human EIF4G1 |
Subcellular Locations | Cytosol Nucleus |
Swiss Prot | Q04637 |
克隆類型 | Polyclonal Antibody |
背景資料 | The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. |
多克隆抗體
由于多克隆抗體通常包含抗某一抗原的不同表位的抗體,所以,在深固定的樣本中也會很好地發(fā)揮效應(yīng),在石蠟包埋組織切片的染色中,多克隆抗體常選用。根據(jù)實驗的不同需要,多克隆抗體應(yīng)用于相應(yīng)抗原的標(biāo)記。此外,在農(nóng)業(yè)生產(chǎn)中,多克隆抗體被用于農(nóng)藥殘留現(xiàn)場監(jiān)測;在臨床應(yīng)用中,多克隆抗體主要用于病原物的檢測、疾病的診斷及治療,如作為蛋白類免疫抑制劑用于移植反應(yīng)和自身免疫病的治療。
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