上海源葉生物科技有限公司

主營產(chǎn)品: S30260異硫氰酸胍,30259鹽酸胍,嗜熱菌蛋白酶

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15921386130

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聯(lián)人:
何小姐
話:
86-021-61559134
機(jī):
15921386130
真:
86-021-55068248
址:
上海市松江區(qū)長(zhǎng)塔路465號(hào)6幢
編:
200433
網(wǎng)址:
www.shyuanye.com
鋪:
http://true-witness.com/st191837/
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S80073
S80073
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更新時(shí)間:2024-07-03 20:17:07瀏覽次數(shù):87

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  • 產(chǎn)品描述: GLP-1(7-36), amide is a physiological incretin hormone that stimulates insulin secretion.
  • 靶點(diǎn): GCGR
  • 體內(nèi)研究: Glucagon-Like Peptide (GLP) I (7-36), amide is a physiological incretin hormone that is released after nutrient intake from the lower gut and stimulates insulin secretion at elevated plasma glucose concentrations. Exogenous GLP-1 (7-36 amide) is an effective means of normalizing fasting plasma glucose concentrations in poorly-controlled Type 2 diabetic subjects. Exogenously administered GLP-1-(7–36)amide is extremely labile in vivo, with more than 80% being cleaved into GLP-1-(9–36)amide after sc or iv administration
  • 參考文獻(xiàn):
    1. Kreymann B, et al. Glucagon-like peptide-1 7-36: a physiological incretin in man. Lancet. 1987 Dec 5;2(8571):1300-4. 2. Mentlein R, et al. Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum. Eur J Biochem. 1993 Jun 15;214(3):829-35. 3. Nauck MA, et al. Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients. Diabetologia. 1993 Aug;36(8):741-4. 4. Hansen L, et al. Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine. Endocrinology. 1999 Nov;140(11):5356-63.
  • 保存條件: -20℃
  • 配置溶液濃度參考:
    1mg 5mg 10mg
    1 mM 0.303 ml 1.516 ml 3.032 ml
    5 mM 0.061 ml 0.303 ml 0.606 ml
    10 mM 0.03 ml 0.152 ml 0.303 ml
    50 mM 0.006 ml 0.03 ml 0.061 ml
  • 注意:部分產(chǎn)品我司僅能提供部分信息,我司不保證所提供信息的性,僅供客戶參考交流研究之用。
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