4-arm-PCL， 4臂聚已內(nèi)酯  6-arm-PCL， 6臂聚已內(nèi)酯

4-arm-PCL， 4臂聚已內(nèi)酯  6-arm-PCL， 6臂聚已內(nèi)酯

4-arm-PCL， 4臂聚已內(nèi)酯  6-arm-PCL， 6臂聚已內(nèi)酯

4-arm-PCL， 4臂聚已內(nèi)酯  6-arm-PCL， 6臂聚已內(nèi)酯

Synthesis Procedure:

Poly (1-Adamantyl acrylate-b-4Vinylpyridine) is obtained by RAFT polymerization process:

Characterization:

The molecular weight and polydispersity index (PDI)

are obtained by size exclusion chromatography (SEC)

using THF as an eluant and HNMR.

Thermal analysis of the samples was carried out using

a differential scanning calorimeter (TA Q100) at a

heating rate of 10oC/min.The inflection glass transition

temperature (Tg) of the sample has been considered.

Poly(ε-caprolactone), 4-arm star polymer / Core: pentaerythritol

4-arm-PCL， 4臂聚已內(nèi)酯

Poly(ε-caprolactone), 6-arm star polymer / Core: dipentaerythritol

6-arm-PCL， 6臂聚已內(nèi)酯

Poly(ε-caprolactone), 6-arm star polymer / Core: trimethylolpropane ethoxylate

Poly(dimethylsiloxane), 2-arm star / Core: Si, functionalized with dansyl amide

Poly(dimethylsiloxane), 3-arm star / Core: Si, functionalized with dansyl amide

Poly(dimethyl siloxane), 3-arm star polymer / Core: silane

Poly(dimethyl siloxane), 3-arm star polymer / Core: 3-silylpropan-1-amine

Poly(isoprene), 3-arm star polymer / Core: 2,4,6-tripropoxy-1,3,5-triazine

Poly(methyl methacrylate), 6-arm star polymer / Core: α-Cyclodextrin

6-arm-PMMA

Poly(methyl methacrylate), 16-arm star polymer / Core: α-Cyclodextrin

Poly(styrene), star polymers / Core: α-Cyclodextrin

Poly(styrene), 10-arm star polymer / Core: diethylene glycol dimethacrylate

10-arm-PS

Poly(styrene), 3-arm star polymer / Core: mesitylene

3-arm-PS

Poly(styrene), 4-arm star polymer / Core: 1,2-bis(methylsilyl)ethane

4-arm-PS

Poly(styrene), 3-arm star polymer / Core: 2,4,6-tripropoxy-1,3,5-triazine

Poly(styrene), 8-arm star polymer / Core: tetrakis(2-silylethyl)silane

8-arm-PS

Poly(styrene), star polymers / Core: oligo([1,2-co-1,4]-butadiene)

Poly(2-vinyl pyridine), 8-arm star polymer / Core: tetrakis(2-silylethyl)silane

8-arm-P2VP

Poly(butadiene)-b-poly(styrene), 4-arm block star / Core: 1,2-bis(methylsilyl)ethane

4-arm PBd-PS

Poly(tert-butyl acrylate)-b-poly(styrene), multi-arm block star / Core: ethylene glycol dimethacrylate

Poly(ε-caprolactone)-b-poly(ethylene oxide), 4-arm block star / Core: pentaerythritol

4-arm PCL-PEO

Poly(ethylene oxide)-b-poly(adipic anhydride), 4-arm block star / Core: pentaerythritol

Poly(ethylene oxide)-b-poly(ε-caprolactone), 4-arm block star / Core: pentaerythritol

4-arm-PEO-PCL

Poly(ethylene oxide)-b-poly(lactide), 4-arm block star / Core: pentaerythritol

4-arm-PEO-PLA

Poly(ethylene oxide)-b-poly(2-methyl oxazoline), 4-arm block star / Core: pentaerythritol

Poly(ethylene oxide)-b-poly(propylene oxide), 4-arm block star / Core: pentaerythritol

Poly(2-hydroxyethyl methacrylate)-b-poly(methyl methacrylate–co–n-butyl methacrylate), 36-arm block star / Core: diethylene glycol dimethacrylate

Poly(lactide)-b-poly(ethylene oxide), 4-arm block star / Core: pentaerythritol

4-arm-PLA-PEO

Poly(methyl methacrylate)-b-poly(styrene), 8-arm block star / Core: α-Cyclodextrin

8-arm-PMMA-PS

Poly(styrene)-b-poly(methyl methacrylate), 14-arm block star / Core: α-Cyclodextrin

Graft Copolymers

四：PEG和多肽氨基酸共聚產(chǎn)品

多聚賴氨酸交聯(lián)聚乙二醇

Poly(L-lysine)-PEG-M

Poly(L-lysine)-PEG-Poly(L-lysine)

Poly(L-lysine)-PEG-NH2

Poly(L-lysine)-PEG-COOH

Poly(L-lysine)-PEG-MAL

Poly(L-lysine)-PEG-NHS

Poly(L-lysine)-PEG-N3

Poly(L-lysine)-PEG-SH

PEG分子量可以選1000、2000、5000 ，多聚賴氨酸分子量可以任意搭配

聚谷氨酸交聯(lián)聚乙二醇

Poly(L-Glutamic acid)-PEG-M

Poly(L-Glutamic acid)-PEG-Poly(L-Glutamic acid)

Poly(L-Glutamic acid)-PEG-NH2

Poly(L-Glutamic acid)-PEG-COOH

Poly(L-Glutamic acid)-PEG-MAL

Poly(L-Glutamic acid)-PEG-NHS

Poly(L-Glutamic acid)-PEG-N3

Poly(L-Glutamic acid)-PEG-SH

PEG分子量可以選1000、2000、5000 ，聚谷氨酸分子量可以任意搭配

聚天冬氨酸交聯(lián)聚乙二醇

Poly(L-aspartic acid)-PEG-M

Poly(L-aspartic acid)-PEG-Poly(L-Glutamic acid)

Poly(L-aspartic acid)-PEG-NH2

Poly(L-aspartic acid)-PEG-COOH

Poly(L-aspartic acid)-PEG-MAL

Poly(L-aspartic acid)-PEG-NHS

Poly(L-aspartic acid)-PEG-N3

Poly(L-aspartic acid)-PEG-SH

PEG分子量可以選1000、2000、5000 ，聚谷氨酸分子量可以任意搭配

五：其他嵌段聚合物產(chǎn)品

mPEG-PLAL   PEG:2000  PLAL:5000

Methoxy poly(ethylene glycol)-b-poly(lactide-co-allyl lactide)

mPEG-PDLLA-COOH   PEG:5000  PDLLA:14000

Methoxy poly(ethylene glycol)-b-poly(D,L-lactic acid)-succinic acid

mPEG-CPLA  PEG:2000 CPLA:5000

Methoxy poly(ethylene glycol)-b-poly(lactide-co-allyl lactide-co-thiolene

conjugated diethylaminoethyl-lactide)

mPEG-PLGA-COOH  PEG:2000  PLGA:2000

Methoxy poly(ethylene glycol)-b-poly(lactide-co-glycolide)-succinic acid

mPEG-PLGA-COOH  PEG:5000  PLGA:5000

Methoxy poly(ethylene glycol)-b-poly(lactide-co-glycolide)-succinic acid

NH2-PLGA-NH2  PLGA:5000    NH2-poly(lactide-co-glycolide)-NH2

P4VP-COOH  (Inherent viscosity (I.V.) = 0.01-0.1 dL/g)

Poly(4-vinylpyridine)-carboxylic acid endcap

P4VP-NHS (Inherent viscosity (I.V.) = 0.01-0.1 dL/g in ethanol at 30°C)

Poly(4-vinylpyridine)-N-hydroxysuccinimide endcap

PAMAM-PLA-COOH  ~15,000Da P(DL)La per arm

Poly(amido amine) 32-arm dendrimer initiated P(DL)La carboxylic acid endcapped star polymer

PS-2C2PD (Mw ~50,000 Da)

Poly(styrene)-(2-cyano-2-propyl dodecyl trithiocarbonate)

PS-PPBD  (8,000 Da)

Poly(styrene)-2-phenyl-2-propyl benzodithioate

PS-TEMPO  (Mn 5,000-10,000 Da)

2,2,6,6-tetramethylpiperidine-N-oxidyl polystyrene

PS-PLA  (Mw ~5,000:5,000 Da)   Poly(styrene)-b-poly(D,L-lactide)

PS-PDLLA (Mw ~45,000:15,000 Da) Poly(styrene)-b-poly(D,L-lactide)

mPEG-PEI  Methoxy poly(ethylene glycol)-b-polyethyleneimine (Mn ~10,000:800 Da)

mPEG-P(5BZTMC)   Methoxy poly(ethylene glycol)-poly(5-benzyloxy-trimethylene carbonate)

(Mw ~5,000:7,000 Da)

mPEG-PTMC  Methoxy poly(ethylene glycol)-poly(trimethylene carbonate)

(Mw ~5,000:7,500 Da)

PLA-PCL-PEG-PCL-PLA Poly(D,L)lactide-b-Polycaprolactone-b-Poly(ethyleneglycol)-b-Polycaprolactone-b-Poly(D,L)lacide  5000-5000-2000-5000-5000

acrylate-PCL-PEG-alk   PEG:5000  PCL:10000

Acrylate-Poly(caprolactone)-b-Poly(ethylene glycol)-alkyne

mPEG-P(DL)La-NH2   PEG:5000  P(DL)La:14000

Methoxy Poly(ethylene glycol)-b-Poly(D,L-lactic acid)-Amine

PDLLA-PEG-CO-NHS  PDLLA:16000  PEG:5000

Poly(D,L-lactide)-b-poly(ethylene glycol)-CONHS

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