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PVP-NH2 氨基修飾聚N-乙烯基吡咯烷酮

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更新時間:2017-11-29 09:50:32瀏覽次數(shù):718

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PVP-NH2 氨基修飾聚N-乙烯基吡咯烷酮
Poly(N-vinyl pyrrolidone), α-amino-terminated
Block copolymers嵌段共聚物是指由2種或2種以上聚合物嵌不同的鏈段的大分子,一般可以分為AB嵌段,ABA嵌段 這2中是二嵌段共聚物,還有三嵌段共聚物如ABC或ABABA等。

PVP-NH2  氨基修飾聚N-乙烯基吡咯烷酮

PVP-NH2  氨基修飾聚N-乙烯基吡咯烷酮

PVP-NH2  氨基修飾聚N-乙烯基吡咯烷酮

PVP-NH2  氨基修飾聚N-乙烯基吡咯烷酮

Poly(N-vinyl pyrrolidone), α-amino-terminated

PVP-NH2  氨基修飾聚N-乙烯基吡咯烷酮

 

Poly(N-vinyl pyrrolidone), α-carboxy-terminated

PVP-COOH  羧基修飾聚N-乙烯基吡咯烷酮

 

Poly(N-vinyl pyrrolidone), α,ω-bis(carboxy)-terminated

COOH-PVP-COOH  羧基-聚N-乙烯基吡咯烷酮-羧基

 

Poly(N-vinyl pyrrolidone), α-hydroxy-terminated

PVP-OH  羥基修飾聚N-乙烯基吡咯烷酮

 

Poly(N-vinyl pyrrolidone), α-mesylate-terminated

 

Poly(N-vinyl pyrrolidone), α-thiol-terminated

PVP-SH 巰基修飾聚N-乙烯基吡咯烷酮

Poly(vinylidene difluoride), α-benzoylchloride-terminated

 

Poly(vinylidene difluoride), α-hydroxy-terminated

 

Poly(vinylidene difluoride), α-trichloromethyl-terminated

 

Poly(1,2-butadiene)-b-poly(ethylene oxide), ω-amino-terminated

聚丁二烯-聚氧乙烯-氨基

 

Poly(1,2-butadiene)-b-poly(ethylene oxide), ω-amino terminated (via amide linkage)

 

Poly(1,2-butadiene)-b-poly(ethylene oxide), ω-Biotin-terminated

聚丁二烯-聚氧乙烯-

 

Poly(1,2-butadiene)-b-poly(ethylene oxide), ω-(tert-butyl propionate)-terminated

 

Poly(1,2-butadiene)-b-poly(ethylene oxide), ω-carboxy-terminated

聚丁二烯-聚氧乙烯-羧基

 

Poly(1,2-butadiene)-b-poly(ethylene oxide), ω-mesylate-terminated

 

Poly(1,2-butadiene)-b-poly(ethylene oxide), ω-(4-methoxybenzyl ester)-terminated

 

Poly(1,2-butadiene)-b-poly(ethylene oxide), ω-(succinic acid)-terminated

 

Poly(1,2-butadiene)-b-poly(ethylene oxide), ω-thiol-terminated

聚丁二烯-聚氧乙烯-巰基

Poly(tert-butyl acrylate)-b-poly(ε-caprolactone), ω-thiol-terminated

PtBA-PCL-SH  聚丙烯酸三丁酯-聚已內(nèi)酯-巰基

 

Poly(2-dimethylaminoethyl methacrylate)-b-poly(ε-caprolactone), ω-thiol-terminated

 

 

Poly(dimethylsiloxane)-b-poly(diphenylsiloxane), ω-amino-terminated

    

Poly(dimethylsiloxane)-b-poly(2-methyloxazoline), ω-amino-terminated


Poly(ethylene oxide)-b-poly(tert-butyl methacrylate), α-amino-terminated, protected end-group

 

Poly(ethylene oxide)-b-poly(tert-butyl methacrylate), α-butoxycarbonylamino-terminated

 

Poly(ethylene oxide)-b-poly(tert-butyl methacrylate), α-tetrahydropyranyl-terminated

 

Poly(ethylene oxide)-b-poly(methacrylic acid), α-amino-terminated

PEO-PMMA-NH2  聚氧乙烯-聚甲基丙烯酸-氨基

 

Poly(ethylene oxide)-b-poly(propylene oxide), ω-bromo-terminated

 

Poly(ethylene oxide)-b-poly(propylene oxide), ω-epoxy-terminated

 

Poly(methacrylic acid)-b-poly(ε-caprolactone), ω-thiol-terminated

PMAA-PCL-SH   聚甲基丙烯酸-聚已內(nèi)酯-巰基

 

Poly(methyl methacrylate)-b-poly(ε-caprolactone), ω-thiol-terminated

PMMA-PCL-SH   聚甲基丙烯酸甲酯-聚已內(nèi)酯-巰基

Poly(methyl methacrylate)-b-poly(styrene), ω-bromo-terminated

 

Poly(methyl methacrylate)-b-poly(styrene), (α-hydroxy, ω-bromo)-terminated; PMMA is atactic

 

Poly(methyl methacrylate)-b-poly(styrene), (α-hydroxy, ω-bromo)-terminated; PMMA is syndiotactic

 

Poly(styrene)-b-poly(1,2-butadiene), α-hydroxy-terminated

 

Poly(styrene)-b-poly(ε-caprolactone), ω-thiol-terminated

PS-PCL-SH  聚苯乙烯-聚已內(nèi)酯-巰基

Poly(styrene)-b-poly(ethylene oxide), α-amino-terminated; with hydroxymethylene at the block junction

 

Poly(styrene)-b-poly(ethylene oxide), ω-bromo-terminated

 

 

Poly(styrene)-b-poly(ethylene oxide), ω-carboxy-terminated

PS-PEO-COOH  聚苯乙烯-聚氧乙烯-羧基

 

Poly(styrene)-b-poly(ethylene oxide), ω-maleimido-terminated

PS-PEO-MAL  聚苯乙烯-聚氧乙烯-馬來酰亞胺

 

Poly(styrene)-b-poly(ethylene oxide), with hydroxymethylene at the block junction

 

Poly(styrene)-b-poly(1,4-isoprene), ω-amino-terminated

 

Poly(styrene)-b-poly(1,4-isoprene), with carbinol group at the block junction

 

Poly(styrene)-b-poly(methyl methacrylate), α-amino-terminated

PS-PMMA-NH2  聚苯乙烯-聚甲基丙烯酸甲酯-氨基

 

Poly(styrene)-b-poly(methyl methacrylate), ω-anthracene-terminated

 

Poly(styrene)-b-poly(methyl methacrylate), α-bromo-terminated

 

Poly(styrene)-b-poly(methyl methacrylate), ω-bromo-terminated

 

Poly(styrene)-b-poly(methyl methacrylate), α-hydroxy-terminated

PS-PMMA-OH  聚苯乙烯-聚甲基丙烯酸甲酯-羥基


Poly(styrene)-b-poly(2-vinyl pyridine), α-hydroxy-terminated

PS-P2VP-OH

 

Poly(styrene)-b-poly(2-vinyl pyridine), ω-hydroxy-terminated

 

Poly(styrene)-b-poly(2-vinyl pyridine), with hydroxy group at the block junction

 

Poly(styrene)-b-poly(2-vinyl pyridine), with silyl group at the block junction


Poly(2-vinyl pyridine)-b-poly(ethylene glycol), α-amino-terminated; with hydroxymethylene at the block junction

 

Poly(2-vinyl pyridine)-b-poly(methyl methacrylate), α-hydroxy-terminated

P2VP-PMMA-OH  聚乙烯基吡啶-聚甲基丙烯酸甲酯-羥基

 

Poly(4-vinyl pyridine)-b-poly(ε-caprolactone), ω-thiol-terminated

P4VP-PCL-SH  聚乙烯基吡啶-聚已內(nèi)酯-巰基

Poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide), α,ω-bis(carboxy)-terminated

 

Poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide), α,ω-bis(epoxy)-terminated

 

Poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide), α-methacrylate-terminated

 

Poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide), (α-methoxy, ω-bromo)-terminated

 

Poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide), (α-methoxy, ω-styrene)-terminated

 

Poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide), α,ω-bis(succinimidyl succinate)-terminated

 

Poly(2-ethyl oxazoline)-b-poly(dimethyl siloxane)-b-poly(2-ethyl oxazoline), α,ω-bis(acrylate)-terminated

 

Poly(2-ethyl oxazoline)-b-poly(dimethyl siloxane)-b-poly(2-ethyl oxazoline), α,ω-bis(methacrylate)-terminated

 

Poly(2-methyl oxazoline)-b-poly(dimethyl siloxane)-b-poly(2-methyl oxazoline), α,ω-bis(acrylate)-terminated

 

Poly(2-methyl oxazoline)-b-poly(dimethyl siloxane)-b-poly(2-methyl oxazoline), α,ω-bis(amino)-terminated

 

Poly(2-methyl oxazoline)-b-poly(dimethyl siloxane)-b-poly(2-methyl oxazoline), α,ω-bis(amino [protected with tert-butoxycarbonyl])-terminated

 

Poly(2-methyl oxazoline)-b-poly(dimethyl siloxane)-b-poly(2-methyl oxazoline), α,ω-bis(carboxy)-terminated

 

Poly(2-methyl oxazoline)-b-poly(dimethyl siloxane)-b-poly(2-methyl oxazoline), α,ω-bis(inosine)-terminated

 

Poly(2-methyl oxazoline)-b-poly(dimethyl siloxane)-b-poly(2-methyl oxazoline), α,ω-bis(maleimido)-terminated

 

Poly(2-methyl oxazoline)-b-poly(dimethyl siloxane)-b-poly(2-methyl oxazoline), α,ω-bis(methacrylate)-terminated

 

以下產(chǎn)品是PEG和PCL和其他活性基團的三嵌段共聚物:

PCL-PEG-OMe

PCL-PEG-PCL

PCL-PEG-MAL

PCL-PEG-COOH

PCL-PEG-NH2

PCL-PEG-NHS

PCL-PEG-Biotin

PCL-PEG-N3

PCL-PEG-SH

PCL-PEG-OH

PCL-PEG-Br

PCL-PEG-Folate

PCL-PEG-Cholesterol

PCL-PEG-OPSS

PCL-PEG-Alkyne

PCL-PEG-Iodoacetamide

acrylate-PCL-PEG-alk  

PCL-PEG-FITC

PCL-PEG-RB

以上的PCL分子量可以自由選擇,PEG分子量有1000,2000,5000的選擇。

可降解的功能分子和多肽氨基酸共聚物

PLGA-Poly(L-lysine)         (聚乳酸-羥基乙酸共聚物交聯(lián)多聚賴氨酸)

PLGA-Poly(L-Glutamic acid)  (聚乳酸-羥基乙酸共聚物交聯(lián)聚谷氨酸)

PLGA-Poly(L-aspartic acid)    (聚乳酸-羥基乙酸共聚物交聯(lián)聚天冬氨酸)

以上的PLGA和聚賴氨酸、聚谷氨酸、聚天冬氨酸的分子量自由組合

 

PLA-Poly(L-lysine)         (聚乳酸共聚物交聯(lián)多聚賴氨酸)

PLA-Poly(L-Glutamic acid)  (聚乳酸共聚物交聯(lián)聚谷氨酸)

PLA-Poly(L-aspartic acid)    (聚乳酸共聚物交聯(lián)聚天冬氨酸)

以上的PLA和聚賴氨酸、聚谷氨酸、聚天冬氨酸的分子量自由組合

 

PCL-Poly(L-lysine)         (聚己內(nèi)酯共聚物交聯(lián)多聚賴氨酸)

PCL-Poly(L-Glutamic acid)  (聚己內(nèi)酯共聚物交聯(lián)聚谷氨酸)

PCL-Poly(L-aspartic acid)    (聚己內(nèi)酯共聚物交聯(lián)聚天冬氨酸)

以上的PCL和聚賴氨酸、聚谷氨酸、聚天冬氨酸的分子量自由組合

 

嵌段共聚物膠束應(yīng)用:

(1)抗膠束

(2)抗膠束

(3)膠束

(4)透過血腦屏障

(5) 傳遞

(6) 包封和傳遞

 

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