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EMCS 異型雙功能交聯(lián)劑 55750-63-5
EMCS 異型雙功能交聯(lián)劑 55750-63-5
產(chǎn)品名稱：EMCS
中文名稱：6-(馬來酰亞胺基)己酸琥珀酰亞胺酯
英文名稱：6-Maleimidohexanoic acid N-hydroxysuccinimide ester
CAS #: 55750-63-5
簡(jiǎn)介：N-(e-Maleimidocaproyloxy)succinimide ester (EMCS) is a non-cleavable, water insoluble, hetero-bifunctional crosslinker that is commonly used to crosslink haptens to carrier proteins and en-zyme to antibody. The EMCS crosslinker spacer arm is longer than GMBS. The EMCS NHS es-ter and maleimide reactive groups react with amino and sulfhydryl moieties, respectively.
N-（e-maleimidocaproyloxy）琥珀酰亞胺酯（EMCS）是不可切割、異型雙功能交聯(lián)劑不溶于水，是的交聯(lián)半抗原載體蛋白和抗體。EMCS交聯(lián)劑間隔臂長(zhǎng)于刺激。EMCS NHS ES TER和馬來酰亞胺基團(tuán)的活性氨基和巰基基團(tuán)反應(yīng)。
Application
A heterobifunctional cross-linking reagent incorporating an extended spacer with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5) The second coupling is specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Contains 9 atom linker. An extended aliphatic spacer stabilizes the maleimide prior to coupling compared to aromatic spacers.
一種異型雙功能交聯(lián)劑將延長(zhǎng)間隔與胺和巰基反應(yīng)。通常情況下，耦合初通過酰胺鍵在pH 7.5緩沖含有伯胺分子（6.5-8.5）耦合是通過硫醚鍵在pH 6.8緩沖含游離巰基的分子比（6.5-7.0）。用于偶聯(lián)物和半抗原載體分子復(fù)合物的制備。包含9個(gè)原子鏈接器。一個(gè)擴(kuò)展的脂肪間隔穩(wěn)定的馬來酰亞胺耦合相比，芳香間隔之前。
結(jié)構(gòu)式：
外觀：白色粉末
Molecular Weight: 308.3
分子式:C14H16N2O6
CAS #: 55750-63-5
溶解度：DMF
Spacer Length: 9.4 Å
Alternative Names: N-(epsilon-Malaimidocaproyloxy) succinimide
純度：98%+
保存：-20℃
：西安瑞禧生物科技有限公司
以上資料源于西安瑞禧生物科技有限公司
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