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南京科佰生物科技有限公司
主營(yíng)產(chǎn)品: atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫購(gòu)買 |
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南京科佰生物科技有限公司
主營(yíng)產(chǎn)品: atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫購(gòu)買 |
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參考價(jià) | 面議 |
更新時(shí)間:2022-07-27 17:26:52瀏覽次數(shù):635
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供貨周期 | 現(xiàn)貨 | 規(guī)格 | T-25 Flask |
---|---|---|---|
貨號(hào) | CBP74070 | 應(yīng)用領(lǐng)域 | 生物產(chǎn)業(yè) |
主要用途 | 僅限科研使用 |
CBP74070 | |
I. Background | |
B7-2 (CD86) signaling through CTLA4 (CD152) has been shown to inhibit T- cell activation. This co-inhibitory pathway can be overactive in many tumors, enabling cancers to escape the host’s immune system. CTLA4-blocking antibodies, including Ipilimumab (Yervoy) and Tremelimumab, have shown clinical efficacy in treating cancer. | |
II. Description | |
Recombinant CHO cells constitutively expressing human CD86. | |
III. Introduction | |
Host Cell: | CHO |
Expressed gene: | CD86 |
Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Synonym(s): | T-lymphocyte activation antigen CD86, B7.2, FUN-1, B70, BU63, CD86, B72 |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | F12K+10%FBS+500ug/ml hygromycin |
Mycoplasma Testing: | Negative |
Storage: | Liquid nitrogen |
Application(s): | Ligand of CD28&Binding Assay,FACS |
IV. Description of Host Cell Line | |
Organism: | Cricetulus griseus, hamster, Chinese |
Tissue: | Ovary |
Disease: | Hamster Chinese ovary |
Morphology: | Epitheloid cell |
Growth Properties: | Adherent |
Ⅴ. Representative Data | |
Figure 1. Recombinant CHO cells expressing human CD86. | |