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公司信息

聯(lián)系人：
蔣經(jīng)理
電話(huà)：
4008750250
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18066071954
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www.co-bioer.com
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www.cobioer.com/
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http://true-witness.com/st281842/
給他留言
CBP74029LIGHT/CHO
LIGHT/CHO
參考價(jià) 面議
具體成交價(jià)以合同協(xié)議為準(zhǔn)
  • 型號(hào) CBP74029
  • 品牌 cobioer/科佰生物
  • 廠(chǎng)商性質(zhì) 代理商
  • 所在地 南京市

更新時(shí)間：2022-07-29 15:48:57瀏覽次數(shù)：672

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【簡(jiǎn)單介紹】
供貨周期 現(xiàn)貨 規(guī)格 T-25 Flask
貨號(hào) CBP74029 應(yīng)用領(lǐng)域 生物產(chǎn)業(yè)
主要用途 僅限科研使用
LIGHT/CHO，凍存條件：90% FBS+10% DMSO；
【詳細(xì)說(shuō)明】
CBP74029
I. Background
LIGHT (TNFSF14) is a key component of the communication system that controls the responses of T-Cells. LIGHT activates two cell surface receptors, the Herpesvirus Entry Mediator (HVEM) and the Lymphotoxin-beta Receptor (LTβR). The LIGHT-HVEM axis is an important costimulatory pathway for T cells, it has been shown to activate NF-κB; LIGHT/HVEM pair are co-stimulatory immune checkpoint molecules for cancer immunotherapy, LIGHT expressing cells have been shown to be more potent than the soluble LIGHT for activating HVEM expressed on T cell surface.

II. Description
Recombinant stable clonal CHO cell line constitutively expressing full length human LIGHT protein, also known as TNFSF14, (Genbank #NM_003807). Surface expression is confirmed by flow cytometry.

III. Introduction
Host Cell:CHO, Chinese Hamster Ovary
Expressed gene:Light
Stability:32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Synonym(s):TNFSF14, light cho
Freeze Medium:90% FBS+10% DMSO
Culture Medium:F12K+10%FBS+300ug/ml hygromycin
Mycoplasma Testing:Negative
Storage:Liquid nitrogen
Application(s):Ligand of HVEM&Binding Assay, FACS

IV. Description of Host Cell Line
Organism:Cricetulus griseus, hamster, Chinese
Tissue:Ovary
Disease: Normal
Morphology: Epitheloid cell
Growth Properties: Adherent

Ⅴ. Representative Data

CBP74029.png

Figure. Recombinant stable clonal CHO cell line constitutively expressing full length human LIGHT protein, also known as TNFSF14, (Genbank #NM_003807). Surface expression is confirmed by flow cytometry.





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