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18066071954

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公司信息

聯(lián)系人：
蔣經(jīng)理
電話：
4008750250
手機(jī)：
18066071954
傳真：
地址：
南京市棲霞區(qū)緯地路9號(hào)
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210000
個(gè)性化：
www.co-bioer.com
網(wǎng)址：
www.cobioer.com/
商鋪：
http://true-witness.com/st281842/
給他留言
CBP74143Claudin18.2/PANC-1
Claudin18.2/PANC-1
參考價(jià) 面議
具體成交價(jià)以合同協(xié)議為準(zhǔn)
  • 型號(hào) CBP74143
  • 品牌 cobioer/科佰生物
  • 廠商性質(zhì) 代理商
  • 所在地 南京市

更新時(shí)間：2022-07-29 14:00:59瀏覽次數(shù)：800

聯(lián)系我們時(shí)請(qǐng)說明是化工儀器網(wǎng)上看到的信息，謝謝!

【簡單介紹】
供貨周期 現(xiàn)貨 規(guī)格 T-25 Flask
貨號(hào) CBP74143 應(yīng)用領(lǐng)域 生物產(chǎn)業(yè)
Claudin18.2/PANC-1
【詳細(xì)說明】


CBP74143
I. Background

Claudins (CLDNs) are a family of proteins that form tight junctions and maintain the polarity of epithelial and endothelial cells. CLDN18 is specifically expressed in the stomach and lung. Of the two CLDN18 isoform transcripts produced by alternative splicing, CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung specific. CLDN18.2 is a highly selective gastric lineage antigen expressed exclusively on short-lived differentiated gastric epithelial cells where it has only limited accessibility to antibody drugs.14,15 CLDN18.2 is maintained during the course of malignant transformation and thus frequently displayed on the surface of human gastric cancer cells.


II. Introduction

Host Cell:

PANC-1

Expressed gene:

Claudin18.2

Stability:32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:90% FBS+10% DMSO
Culture Medium:DMEM+10%FBS+2ug/ml puromycin
Mycoplasma Testing:Negative
Storage:Liquid nitrogen
Application(s):Binding Assay,FACS

III. Description of Host Cell Line
Species:Human
Disease: A human pancreatic Beta cell: PANC-1 hybrid cell line. Insulin-secreting cell line.
Morphology: Epithelial
Growth Properties: Adherent

IV. Representative Data

1. Claudin18.2/PANC-1








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