南京科佰生物科技有限公司
主營產(chǎn)品: atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫購買 |
聯(lián)系電話
南京科佰生物科技有限公司
主營產(chǎn)品: atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫購買 |
聯(lián)系電話
參考價(jià) | ¥ 900 |
訂貨量 | 1件 |
更新時(shí)間:2022-11-25 14:47:19瀏覽次數(shù):433
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供貨周期 | 現(xiàn)貨 | 規(guī)格 | 1ug |
---|---|---|---|
貨號(hào) | CBP10446 | 應(yīng)用領(lǐng)域 | 生物產(chǎn)業(yè) |
CBP10446 | |
Gene | APC |
Description | APC, adenomatous polyposis coli, is a tumor suppressor (PMID: 30562755) and multi-domain protein regulating numerous cellular functions through interaction with beta-catenin and subsequent inhibition of Wnt signalling (PMID: 21502284). APC germline mutations are associated with familial adenomatous polyposis (PMID: 30562755) and somatic mutations with colon, endometrial, NSCLC, and breast cancers (PMID: 27283171). |
Technical Data | |
DNA Change | c.4290delC |
AA Change | p.T1430fs |
Mutation type | Frame_Shift_Del |
Zygosity | Heterozygous |
Allelic Frequency | 66.66% |
Transcript | ENST00000457016.1 |
Cosmic ID | COSM19052 |
Chr position(GRCh37) | chr5:112175581 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |