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南京科佰生物科技有限公司
主營(yíng)產(chǎn)品： atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫(kù)購(gòu)買 |
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南京科佰生物科技有限公司
主營(yíng)產(chǎn)品： atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫(kù)購(gòu)買 |
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| 參考價(jià) | 面議 |
更新時(shí)間：2022-09-16 09:44:18瀏覽次數(shù)：623
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| 供貨周期 | 現(xiàn)貨 | 規(guī)格 | 1ug |
|---|---|---|---|
| 貨號(hào) | CBP10335 | 應(yīng)用領(lǐng)域 | 生物產(chǎn)業(yè) |
CBP10335 | |
| Format | Genomic DNA |
| Description | EGFR E746_A750del results in the deletion of five amino acids in the kinase domain of the Egfr protein from amino acids 746 to 750 (PMID: 17318210). E746_A750del results in increased Egfr kinase activity, activation of p44/42 MAPK and AKT in cell culture, promotes tumor growth in xenograft models (PMID: 16373402, PMID: 16912195), and is transforming in cell culture (PMID: 29533785). |
| Technical Data | |
| DNA Change | c.2236_2250del15 GAATTAAGAGAAGCA>- |
| AA Change | p.E746_A750delELREA |
| Mutation type | Deletion - In frame |
| Zygosity | Heterozygous |
| Allelic Frequency | 97.3% |
| Transcript | ENST00000275493 |
| Cosmic ID | COSM6225 |
| Chr position(GRCh37) | chr7:55242466_55242480 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
