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南京科佰生物科技有限公司
主營產品： atcc代理,ATCC細胞系,ATCC細胞株,ATCC細胞庫購買 |
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聯(lián)系電話
|
南京科佰生物科技有限公司
主營產品： atcc代理,ATCC細胞系,ATCC細胞株,ATCC細胞庫購買 |
聯(lián)系電話
| 參考價 | 面議 |
更新時間：2022-09-16 11:51:51瀏覽次數(shù)：596
聯(lián)系我們時請說明是化工儀器網(wǎng)上看到的信息，謝謝!
CBP10293 | |
| Format | Genomic DNA |
| Description | KRAS G12V is a hotspot mutation that lies within a GTP binding region of the Kras protein (UniProt.org). G12V results in decreased Kras GTPase activity and increased activation of downstream signaling in cell culture, and leads to increased tumor growth in mouse models (PMID: 23455880, PMID: 26037647, PMID: 24642870) and is transforming in cell culture (PMID: 29533785). |
| Technical Data | |
| DNA Change | c.35G>T |
| AA Change | p.G12V |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | ENST00000311936 |
| Cosmic ID | COSM520 |
| Chr position(GRCh37) | chr12:25398284 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
