南京科佰生物科技有限公司
主營產(chǎn)品: atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫購買 |
聯(lián)系電話
南京科佰生物科技有限公司
主營產(chǎn)品: atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫購買 |
聯(lián)系電話
參考價(jià) | 面議 |
更新時間:2022-10-28 14:46:55瀏覽次數(shù):429
聯(lián)系我們時請說明是化工儀器網(wǎng)上看到的信息,謝謝!
供貨周期 | 現(xiàn)貨 | 規(guī)格 | 1ug |
---|---|---|---|
貨號 | CBP10452 | 應(yīng)用領(lǐng)域 | 生物產(chǎn)業(yè) |
CBP10452 | |
Gene | NOTCH1 |
Description | NOTCH1, neurogenic locus notch homolog protein 1, is a transmembrane receptor, which plays a role in cell fate determination, growth, survival (PMID: 25388163) and chemoresistance (PMID: 29998084). Activating Notch1 mutations are common in T-cell lymphoblastic leukemia/lymphoma (PMID: 22006338, PMID: 30103821), chronic lymphocytic leukemia (PMID: 29998084) and amplification and/or overexpression has been observed in bladder (PMID: 29643502), colorectal (PMID: 30136202, PMID: 30043645), and gastric cancers (PMID: 30043645). |
Technical Data | |
DNA Change | c.4159_4160insAATGCCAGTTCCCG |
AA Change | p.A1387fs |
Mutation type | Frame_Shift_Ins |
Zygosity | Heterozygous |
Allelic Frequency | 50.00% |
Transcript | ENST00000277541.6 |
Cosmic ID | N/A |
Chr position(GRCh37) | chr9:139400189_139400188 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |