南京科佰生物科技有限公司
主營產(chǎn)品: atcc代理,ATCC細胞系,ATCC細胞株,ATCC細胞庫購買 |
聯(lián)系電話
南京科佰生物科技有限公司
主營產(chǎn)品: atcc代理,ATCC細胞系,ATCC細胞株,ATCC細胞庫購買 |
聯(lián)系電話
參考價 | 面議 |
更新時間:2022-09-21 10:28:54瀏覽次數(shù):404
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供貨周期 | 現(xiàn)貨 | 規(guī)格 | 1ug |
---|---|---|---|
貨號 | CBP10186 | 應(yīng)用領(lǐng)域 | 生物產(chǎn)業(yè) |
CBP10186 | |
Format | Genomic DNA |
Description | TP53 R280K lies within the DNA-binding domain of the Tp53 protein (PMID: 22713868). R280K results in decreased activation and repression of wild-type Tp53 target genes (PMID: 17070499, PMID: 16322760, PMID: 18472962), as well as a gain-of-function in activation of novel targets, and leads to increased cell migration and invasion, and increased cell survival (PMID: 18472962, PMID: 24763051). |
Technical Data | |
DNA Change | c.839G>A |
AA Change | p.R280K |
Mutation type | Substitution - Missense |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | ENST00000269305 |
Cosmic ID | COSM10728 |
Chr position(GRCh37) | chr17:7577099 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | Download for COA |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |