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CRO001-Crotamine響尾蛇胺
【產(chǎn)品簡(jiǎn)介】
【詳細(xì)說(shuō)明】
Crotamine響尾蛇胺
Cell-penetrating peptide and ion channels blocker
細(xì)胞穿透肽和離子通道阻斷劑
Crotamine is a basic peptide present in the venom of the South American rattlesnake Crotalus durissus terrificus. Multiple biological functions have been attributed to Crotamine. It is a natural cell-penetrating peptide with selective biological action towards actively proliferating cell types. Moreover, it has been reported that crotamine is a blocker of Kv1.3 (IC50 around 300 nM) as well as Kv1.1 and Kv1.2. It has analgesic properties and myonecrotic effects. In addition, crotamine belongs to the beta-defensin peptides and as such demonstrates antibacterial properties by interacting with lipid membranes.
Crotamine響尾蛇胺技術(shù)資料
氨基酸序列:
YKQCHKKGGHCFPKEKICLPPSSDFGKMDCRWRWKCCKKGSG-OH
二硫鍵:Cys4-Cys36; Cys11-Cys30; Cys18-Cys37
長(zhǎng)度 (aa): 41
分子式: C214H326N64O54S7
分子量:4883.82 Da
外觀:White lyophilized solid
可溶性: water or saline buffer
CAS 號(hào):
來(lái)源:Synthetic
純度:> 95%
產(chǎn)品信息
貨號(hào) | 名稱(chēng) | 規(guī)格 |
CRO001 | Crotamine響尾蛇胺 | 100ug/500ug/1000ug |
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