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英文名稱 AGFG1
中文名稱 艾滋病病毒復制結合蛋白抗體
別 名 HIV 1 Rev binding protein; RAB; Rev/Rex activation domain-binding protein; RIP; AGFG1; AGFG1_HUMAN; Arf-GAP domain and FG repeats-containing protein 1; ArfGAP with FG repeats 1; HIV-1 Rev-binding protein; HRB; Nucleoporin like protein RIP; Nucleoporin-like protein RIP; Rev interacting protein; Rev-interacting protein.
艾滋病病毒復制結合蛋白抗體
說 明 書 0.2ml
研究領域 細胞生物 免疫學 信號轉導 細菌及病毒
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Horse,
產品應用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 58kDa
細胞定位 細胞核 細胞漿
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human AGFG1
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.
Function:
Required for vesicle docking or fusion during acrosomebiogenesis (By similarity). May play a role in RNA trafficking orlocalization. In case of infection by HIV-1, acts as a cofactor forviral Rev and promotes movement of Rev-responsiveelement-containing RNAs from the nuclear periphery to thecytoplasm. This step is essential for HIV-1 replication.
Subunit:
Interacts with EPS15R and EPS15. Interacts with FCHO1.
Subcellular Location:
Nucleus. Cytoplasmic vesicle.
Tissue Specificity:
Ubiquitously expressed.
Post-translational modifications:
O-glycosylated (By similarity).
Similarity:
Contains 1 Arf-GAP domain.
Database links:
UniProtKB/Swiss-Prot: P52594.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.xy-2415R Ankyrin G錨定蛋白G抗體
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