心肌錨蛋白重復(fù)結(jié)構(gòu)域1抗體 返回列表頁

英文名稱 ANKRD1
中文名稱 心肌錨蛋白重復(fù)結(jié)構(gòu)域1抗體
別    名 ALRP; ANKR1_HUMAN; ANKRD 1; ANKRD1; Ankyrin repeat domain 1 (cardiac muscle); Ankyrin repeat domain containing protein 1; Ankyrin repeat domain-containing protein 1; C 193; C193; Cardiac ankyrin repeat protein; CARP; CVARP; Cytokine inducible nuclear protein; Cytokine-inducible gene C-193 protein; Cytokine-inducible nuclear protein; HA1A2; Liver ankyrin repeat domain 1; MCARP.
心肌錨蛋白重復(fù)結(jié)構(gòu)域1抗體  
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  心血管  細胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
細胞定位 細胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ANKRD1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.

Function:
May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.

Subunit:
Interacts with YBX1 (By similarity). Interacts with TTN/titin.

Subcellular Location:
Nucleus.

Tissue Specificity:
Mainly expressed in activated vascular endothelial cells. To a lower extent, also expressed in hepatoma cells.

DISEASE:
Defects in ANKRD1 may be a cause of total anomalous pulmonary venous return (TAPVR) . TAPVR is a rare congenital heart disease (CHD) in which the pulmonary veins fail to connect to the left atrium during cardiac development, draining instead into either the right atrium or one of its venous tributaries. This disease accounts for 1.5% of all CHDs and has a prevalence of approximay 1 out of 15'000 live births.

Similarity:
Contains 5 ANK repeats.

Gene ID:
27063

Database links:

Entrez Gene: 27063 Human

Entrez Gene: 107765 Mouse

Entrez Gene: 27064 Rat

Omim: 609599 Human

SwissProt: Q15327 Human

SwissProt: Q9CR42 Mouse

SwissProt: Q8R560 Rat

Unigene: 448589 Human

Unigene: 10279 Mouse

Unigene: 3789 Ratxy-2771R AMPK alpha 2腺苷單磷酸活化蛋白激酶α2抗體
xy-2778R ADK腺苷酸激酶抗體
xy-13780R A2ML1α2巨球蛋白樣蛋白1抗體 α2ML1
xy-13814R APR3細胞凋亡相關(guān)蛋白3抗體
xy-10196R Actin肌動蛋白α/α-SMA/α Actin抗體
xy-12331R ABCB7ATP結(jié)合蛋白家族7抗體
xy-12349R ASCL2ASCL2蛋白抗體
xy-12534R phospho-Ataxin 1(Ser775)磷酸化脊髓小腦失調(diào)癥蛋白1抗體
xy-12535R phospho-ATF1 (Ser63)磷酸化活化轉(zhuǎn)錄因子1抗體
xy-12536R phospho-ATF2 (Ser480)磷酸化活化復(fù)制因子2抗體
xy-12537R phospho-ATF2 (Thr51 + Thr53)磷酸化活化復(fù)制因子2抗體
xy-12538R phospho-ATF2 (Thr69 + Thr51)磷酸化活化復(fù)制因子2抗體
xy-12539R phospho-ATF2 (Thr73 + Thr55)磷酸化活化復(fù)制因子2抗體
xy-12541R phospho-ATF2 (Thr71 + Thr53)磷酸化活化復(fù)制因子2抗體
xy-12540R phospho-ATF2(Thr71)磷酸化活化復(fù)制因子2抗體
xy-12542R ATF5活化轉(zhuǎn)錄因子5抗體
xy-12543R ATF6 beta活化轉(zhuǎn)錄因子6β抗體
xy-12544R ATICAICAR甲?；D(zhuǎn)移酶抗體
xy-12545R phospho-ATM (Ser794)磷酸化毛細血管擴張性共濟失調(diào)癥突變蛋白抗體
xy-12546R ATP5EATP5E蛋白抗體
xy-12547R ATP5G2ATP5G2蛋白抗體
xy-12548R ATP6V0D2ATP6V0D2蛋白抗體
xy-12549R ATP6V1B2ATP6V1B2蛋白抗體
xy-12550R ATPIF1ATPIF1蛋白抗體
xy-12551R AttractinAttractin蛋白抗體
xy-12552R Phospho-Aurora B(Tyr12)磷酸化有絲分裂激酶B抗體
xy-12529R ARPM1肌動蛋白相關(guān)蛋白M1抗體