錨蛋白重復域53抗體 返回列表頁

英文名稱 ANKRD53
中文名稱 錨蛋白重復域53抗體
別    名 ANKRD 53; ANKRD53; Ankyrin repeat domain containing protein 53; Ankyrin repeat domain-containing protein 53; ANR53_HUMAN; FLJ12056.
 錨蛋白重復域53抗體
說 明 書 0.2ml  
研究領域 細胞生物  免疫學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60 kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ANKRD54
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
 產(chǎn)品介紹 background:
Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD53 (ankyrin repeat domain 53) is a 530 amino acid protein that contains three ANK repeats. Conserved in chimpanzee, dog, cow, mouse and zebrafish, ANKRD53 is encoded by a gene that maps to human chromosome 2p13.3. As the second largest human chromosome, chromosome 2 makes up approximay 8% of the human genome and contains 237 million bases encoding over 1,400 genes. Chromosome 2 contains a probable vestigial second centromere, as well as vestigial omeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.

Similarity:
Contains 4 ANK repeats.

Database links:
 

UniProtKB/Swiss-Prot: Q6NXT1.2

Important Note:
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