含錨蛋白重復(fù)序列-細(xì)胞因子信號(hào)抑制物盒蛋白家族9抗體 返回列表頁(yè)

英文名稱 ASB9
中文名稱 含錨蛋白重復(fù)序列-細(xì)胞因子信號(hào)抑制物盒蛋白家族9抗體
別    名 Ankyrin repeat and SOCS box protein 9; ASB 9; ASB-9; ASB9_HUMAN.
 含錨蛋白重復(fù)序列-細(xì)胞因子信號(hào)抑制物盒蛋白家族9抗體 
說(shuō) 明 書(shū) 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ASB9
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
 產(chǎn)品介紹 background:
This gene encodes a member of the ankyrin repeat and suppressor of cytokine signaling (SOCS) box protein family. Members of this family can interact with the elongin B-C adapter complex via their SOCS box domain and further complex with the cullin and ring box proteins to form E3 ubiquitin ligase complexes. They may function to mediate the substrate-recognition of the E3 ubiquitin ligases. A transcribed pseudogene of this gene has been identified on chromosome 15. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].

Function:
Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A.

Subcellular Location:
Mitochondrion.

Tissue Specificity:
Predominantly expressed in testis, kidney, and liver.

Similarity:
Contains 6 ANK repeats.
Contains 1 SOCS box domain.

Database links:
UniProtKB/Swiss-Prot: Q96DX5.1

Important Note:
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