腎上腺皮質(zhì)線粒體鐵氧還蛋白抗體 返回列表頁(yè)

英文名稱 Adrenodoxin
中文名稱 腎上腺皮質(zhì)線粒體鐵氧還蛋白抗體
別    名 Adrenal ferredoxin; Adrenodoxin; Adrenodoxin, mitochondrial; ADX; ADX_HUMAN; FDX; fdx1; Ferredoxin 1; Ferredoxin-1; Hepatoredoxin; LOH11CR1D; Mitochondrial adrenodoxin; mitochondrial.
 腎上腺皮質(zhì)線粒體鐵氧還蛋白抗體
  
說 明 書 0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  生長(zhǎng)因子和激素  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 13.5kDa
細(xì)胞定位 細(xì)胞漿 線粒體
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Adrenodoxin/FDX (51-150aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
 
產(chǎn)品介紹 background:
This gene encodes a small iron-sulfur protein that transfers electrons from NADPH through ferredoxin reductase to mitochondrial cytochrome P450, involved in steroid, vitamin D, and bile acid metabolism. Pseudogenes of this functional gene are found on chromosomes 20 and 21. [provided by RefSeq, Aug 2011]

Function:
Participates in the synthesis of thyroid hormones. Transfers electrons from adrenodoxin reductase to the cholesterol side chain cleavage cytochrome P450.

Subcellular Location:
Mitochondrion matrix.

Tissue Specificity:
Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level).

Similarity:
Belongs to the adrenodoxin/putidaredoxin family.
Contains 1 2Fe-2S ferredoxin-type domain.

Database links:

Entrez Gene: 2230 Human

Entrez Gene: 14148 Mouse

Entrez Gene: 29189 Rat

Omim: 103260 Human

SwissProt: P10109 Human

SwissProt: P46656 Mouse

SwissProt: P24483 Rat

Unigene: 744 Human

Unigene: 1061 Mouse

Unigene: 440190 Mouse

Unigene: 6946 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
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