鐵蛋白Fe65樣蛋白1抗體 返回列表頁(yè)

英文名稱 APBB2
中文名稱 鐵蛋白Fe65樣蛋白1抗體
別    名 Amyloid beta (A4) precursor protein-binding, family B, member 2 (Fe65 like); Amyloid beta A4 precursor protein binding family B member 2; Amyloid beta A4 precursor protein-binding family B member 2; APBB 2; APBB2; APBB2_HUMAN; Fe65 like 1; Fe65 like; Fe65 like protein; FE65L 1; FE65L; FE65L1; Protein Fe65-like 1; Rirl 1; Rirl1; TR2 L; TR2L; Zfra; Zinc finger like protein.
鐵蛋白Fe65樣蛋白1抗體  
說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  Alzheimer's  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 83kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human APBB2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Function:
May modulate the internalization of beta-amyloid precursor protein.

Subunit:
Binds to the intracellular domain of the beta-amyloid precursor protein.

Similarity:
Contains 2 PID domains.
Contains 1 WW domain.

Database links:

Entrez Gene: 323 Human

Entrez Gene: 11787 Mouse

Omim: 602710 Human

SwissProt: Q92870 Human

SwissProt: Q9DBR4 Mouse

Unigene: 479602 Human

Unigene: 482700 Mouse

Unigene: 5159 Mouse

Important Note:
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