KMT2H蛋白抗體 返回列表頁

英文名稱 ASH1L
中文名稱 KMT2H蛋白抗體
別    名 KMT2H / ASH1; KMT2H; ASH1; Absent small and homeotic disks protein 1 homolog; Absent Small or Homeotic Like; ASH 1 ; ASH 1L; ash1 (absent small or homeotic 1); Ash1 (absent small or homeotic) like ; ASH1-like protein; ASH1L; ASH1L_HUMAN; ASH1L1; FLJ10504; huASH1; KIAA1420; Lysine N-methyltransferase 2H; Probable histone-lysine N-methyltransferase ASH1L.
KMT2H蛋白抗體   
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
產(chǎn)品應(yīng)用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 333kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human KMT2H/ASH1L
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

產(chǎn)品介紹 background:
This gene encodes a member of the trithorax group of transcriptional activators. The protein contains four AT hooks, a SET domain, a PHD-finger motif, and a bromodomain. It is localized to many small speckles in the nucleus, and also to cell-cell tight junctions. [provided by RefSeq, Jul 2008]

Function:
Histone methyltransferase. Probably methylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation.

Subcellular Location:
Nucleus.

Tissue Specificity:
Widely expressed, with highest level in brain, heart and kidney.

Similarity:
Belongs to the histone-lysine methyltransferase family. SET2 subfamily.
Contains 3 A.T hook DNA-binding domains.
Contains 1 AWS domain.
Contains 1 BAH domain.
Contains 1 bromo domain.
Contains 1 PHD-type zinc finger.
Contains 1 post-SET domain.
Contains 1 SET domain.

Database links:

Entrez Gene: 55870 Human

Omim: 607999 Human

SwissProt: Q9NR48 Human

Unigene: 491060 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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