釉基質(zhì)蛋白抗體 返回列表頁

英文名稱 AMBN
中文名稱 釉基質(zhì)蛋白抗體
別    名 AMBN; AMBN_HUMAN; Ameloblastin (enamel matrix protein); Ameloblastin.
釉基質(zhì)蛋白抗體   
說 明 書 0.1ml  0.2ml  
研究領域 細胞生物  信號轉(zhuǎn)導  細胞骨架  細胞外基質(zhì)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
細胞定位 細胞外基質(zhì) 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human AMBN
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Dental enamel is a highly mineralized tissue with most of its volume occupied by large, highly organized, hydroxyapatite crystals. This structure is thought to be controlled through the interaction of many organic matrix molecules including amelogenin, ameloblastin, enamelin, tufin and several other enzymes. All of these secreted proteins are involved in the mineralization and enamel matrix formation in developing tooth enamel. Ameloblastin (AMBN), which localizes to the extracellular matrix, is an ameloblast-specific protein. It is detected in the sheath space between rod-interrod enamel and at the Tomes processes of secretory ameloblasts. Defects in the gene encoding for ameloblastin, AMBN, can be seen in patients with ameloblastomas.

Function:
Involved in the mineralization and structural organization of enamel.

Subcellular Location:
Secreted > extracellular space > extracellular matrix.

Tissue Specificity:
Ameloblast-specific. Located at the Tomes processes of secretory ameloblasts and in the sheath space between rod-interrod enamel.

Similarity:
Belongs to the ameloblastin family.

Database links:
UniProtKB/Swiss-Prot: Q9NP70.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.xy-0668R Met (c Met)肝細胞生長因子受體抗體
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