自噬相關(guān)蛋白8A抗體 返回列表頁(yè)

英文名稱(chēng) APG8A
中文名稱(chēng) 自噬相關(guān)蛋白8A抗體
別    名 APG8A (autophagy 8A); AT4G21980; ATG8; ATG8A; Autophagy 8A; Autophagy related protein 8a; Autophagy related ubiquitin like modifier ATG8a; F1N20.80; F1N20_80; ATG8A_ARATH.
自噬相關(guān)蛋白8A抗體   
說(shuō) 明 書(shū) 0.2ml  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)運(yùn)蛋白  表觀遺傳學(xué)  泛素  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Arabidopsis thaliana
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 13kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from Arabidopsis thaliana APG8A
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
產(chǎn)品介紹 background:
APG8A is involved in cytoplasm to vacuole transport (Cvt) vesicles and autophagosomes formation. It may mediate the delivery of the vesicles and autophagosomes to the vacuole via the microtubule cytoskeleton.

Function:
Involved in cytoplasm to vacuole transport (Cvt) vesicles and autophagosomes formation. May mediate the delivery of the vesicles and autophagosomes to the vacuole via the microtubule cytoskeleton.

Subunit:
Interacts with ATG4b.

Subcellular Location:
Cytoplasmic vesicle ?cvt vesicle membrane; Lipid-anchor. Cytoplasmic vesicle ?autophagosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor. Note= Membrane-associated through a lipid anchor.

Post-translational modifications:
The C-terminal 5 residues are removed by ATG4 to expose Gly-117 at the C-terminus. This Gly-117 forms then a thioester bond with the 'Cys-558' of ATG7 (E1-like activating enzyme) before being transferred to the 'Cys-258' of ATG3 (the specific E2 conjugating enzyme), in order to be finally amidated with phosphatidylethanolamine. This lipid modification anchors ATG8 to autophagosomes (By similarity).

Similarity:
Belongs to the MAP1 LC3 family.

Database links:
UniProtKB/Swiss-Prot: Q8LEM4.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.xy-11422R Neuropeptide S神經(jīng)肽S抗體
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