三號(hào)染色體開放閱讀框抗體 返回列表頁

英文名稱 APRG1
中文名稱 三號(hào)染色體開放閱讀框抗體
別    名 AP20 region protein 1; APRG1; APRG1_HUMAN; C3orf35; chromosome 3 open reading frame 35.
三號(hào)染色體開放閱讀框抗體  
說 明 書 0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  細(xì)胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 19kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human APRG1/C3orf35
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
APRG1 is a 170 amino acid single-pass membrane protein that exists as 3 alternatively spliced isoforms. APRG1 isoform 1 is highly expressed in placenta and pancreas, while isoform 2 is mainly expressed in kidney. The gene encoding APRG1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.

Subcellular Location:
Membrane; Single-pass membrane protein (Potential).

Tissue Specificity:
Isoform 1 is expressed at high levels in the pancreas and placenta. Isoform 2 is expressed at high levels in the kidney.

Database links:

Entrez Gene: 339883 Human

Omim: 611429 Human

SwissProt: Q8IVJ8 Human

Unigene: 475945 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.xy-11255R NSFN-乙基順丁烯二酰亞胺敏感融合蛋白抗體
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