磷酸化促凋亡Bik蛋白抗體 返回列表頁

英文名稱 phospho-Bik(Thr33)
中文名稱 磷酸化促凋亡Bik蛋白抗體
別    名 Bik (phospho T33); p-Bik (phospho T33); Apoptosis inducer NBK; BBC1; Bcl-2-interacting killer; BCL2 interacting killer; bhikhari; BIK; Bik-like killer protein; BIK_HUMAN; BIP 1; BIP1; BP 4; BP4; cb 60; NBK.
磷酸化促凋亡Bik蛋白抗體說 明 書 0.1ml  
產品類型 磷酸化抗體 
研究領域 細胞生物  免疫學  細胞凋亡  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 18kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human Bik around the phosphorylation site of Thr33
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK.

Function:
Accelerates programmed cell death. Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX.

Subunit:
Interacts with RHBDL4/RHBDD1.

Subcellular Location:
Endomembrane system; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein (By similarity). Note=Around the nuclear envelope, and in cytoplasmic membranes.

Post-translational modifications:
Proteolytically cleaved by RHBDL4/RHBDD1. RHBDL4/RHBDD1-induced cleavage is a necessary step prior its degradation by the proteosome-dependent mechanism.

Database links:
UniProtKB/Swiss-Prot: Q13323.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.xy-6037R CPEB1細胞質多聚腺苷酸結合蛋白1抗體
xy-6039R CST7半胱氨酸蛋白酶抑制劑7抗體
xy-15135R C22orf2922號染色體開放閱讀框29抗體
xy-2667R Contactin-1神經細胞表面蛋白F3
xy-2672R Cathepsin C/DPP1組織蛋白酶C抗體
xy-0082R Caspase 4半胱胺酸蛋白酶蛋白-4抗體
xy-0087R caspase-3 p12 subunit活化半胱胺酸蛋白酶蛋白3抗體
xy-15276R C7ORF617號染色體開放閱讀框61抗體
xy-2183R Claudin 11少突膠質細胞跨膜蛋白抗體
xy-2211R CD80刺激分子B7-1蛋白抗體
xy-2673R C5b-9末端補體復合物抗體
xy-15296R C8orf558號染色體開放閱讀框55抗體
xy-15186R C4a+C4b補體C4a+C4b蛋白抗體
xy-2779R CD44v7CD44V7抗體
xy-2780R CD44v10CD44V10抗體
xy-2783R CD44v4CD44V4抗體
xy-2790R Claudin 4緊密連接蛋白4抗體
xy-15221R C6orf1406號染色體開放閱讀框140抗體
xy-2776R CACH2L型鈣通道蛋白抗體
xy-2781R CACNA1G電壓依賴性鈣通道Cav3.1抗體
xy-2788R Claudin 3緊密連接蛋白3抗體
xy-3172R phospho-c-Jun (Ser73)磷酸化原癌基因c-Jun抗體
xy-3173R phospho-c-Jun(Ser243)磷酸化原癌基因c-Jun抗體
xy-15079R C1orf861號染色體開放閱讀框86抗體
xy-15298R C8ORF598號染色體開放閱讀框59抗體