膽鹽激活脂肪酶抗體 返回列表頁(yè)

英文名稱(chēng) Bile salt-activated lipase
中文名稱(chēng) 膽鹽激活脂肪酶抗體
別    名 BAL; Bile salt-stimulated lipase; BSDL; BSSL; Bucelipase; Carboxyl ester lipase (bile salt stimulated lipase); Carboxyl ester lipase; CEase; CEL; CELL; Cholesterol esterase; FAP; FAPP; Fetoacinar pancreatic protein; LIPA; Lysophospholipase, pancreatic; MODY8. Pancreatic lysophospholipase; Sterol esterase antibody; CEL_HUMAN.
膽鹽激活脂肪酶抗體    
說(shuō) 明 書(shū) 0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  轉(zhuǎn)運(yùn)蛋白  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 81kDa
細(xì)胞定位 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Bile salt-activated lipase (151-180aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat(VNTR) polymorphism in the coding region that may influence the function of the encoded protein. [provided by RefSeq].

Function:
Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides.

Subcellular Location:
Secreted.

Tissue Specificity:
Mammary gland and pancreas.

DISEASE:
Defects in CEL are a cause of maturity-onset diabetes of the young type 8 with exocrine dysfunction (MODY8) [MIM:609812]; also known as diabetes and pancreatic exocrine dysfunction (DPED). MODY is a form of diabetes that is characterized by an autosomal dominant mode of inheritance, onset in childhood or early adulthood (usually before 25 years of age), a primary defect in insulin secretion and frequent insulin-independence at the beginning of the disease.

Similarity:
Belongs to the type-B carboxylesterase/lipase family.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.xy-15096R C20orf15120號(hào)染色體開(kāi)放閱讀框151抗體
xy-15117R c20orf7820號(hào)染色體開(kāi)放閱讀框78抗體
xy-15103R C20orf18720號(hào)染色體開(kāi)放閱讀框187抗體
xy-15126R C21orf5921號(hào)染色體開(kāi)放閱讀框59抗體
xy-15097R C20orf152 20號(hào)染色體開(kāi)放閱讀框152抗體
xy-15098R C20orf16520號(hào)染色體開(kāi)放閱讀框165抗體
xy-15099R C20orf16620號(hào)染色體開(kāi)放閱讀框166抗體
xy-15100R C20orf17320號(hào)染色體開(kāi)放閱讀框173抗體
xy-15106R C20orf2420號(hào)染色體開(kāi)放閱讀框24抗體
xy-15109R C20orf30 20號(hào)染色體開(kāi)放閱讀框30抗體
xy-15111R C20orf420號(hào)染色體開(kāi)放閱讀框4抗體
xy-15113R C20orf720號(hào)染色體開(kāi)放閱讀框7抗體
xy-15118R C20orf79 20號(hào)染色體開(kāi)放閱讀框79抗體
xy-15119R C20orf9420號(hào)染色體開(kāi)放閱讀框94抗體
xy-15125R C21orf3721號(hào)染色體開(kāi)放閱讀框37抗體
xy-15132R C22orf15 22號(hào)染色體開(kāi)放閱讀框15抗體
xy-15131R C22orf1322號(hào)染色體開(kāi)放閱讀框13抗體
xy-15134R C22orf2622號(hào)染色體開(kāi)放閱讀框26抗體
xy-15142R C2b補(bǔ)體C2b鏈多肽抗體
xy-15147R C2orf162號(hào)染色體開(kāi)放閱讀框16抗體
xy-15148R C2orf27 2號(hào)染色體開(kāi)放閱讀框27抗體
xy-12989R phospho-delta 1 Catenin (Ser268)磷酸化δ連環(huán)蛋白抗體
xy-12990R phospho-delta 1 Catenin (Thr310)磷酸化δ連環(huán)蛋白抗體
xy-12991R phospho-delta 1 Catenin (Thr916)磷酸化δ連環(huán)蛋白抗體