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CD38 抗體

抗原
CD38
別名 Cd38-rs1, T10
適用
其他選擇 Murine
Human(226),Murine (139),Rat (Rattus) (12),Monkey (1)
宿主
其他選擇 Rat
Mouse(169),Rat (117),Rabbit (79),Goat (2)
克隆類型 (克隆位點)
Monoclonal (NIMR-5)
標記
其他選擇 FITC
PE(48),FITC (40),Biotin (36),APC (21),Cy5,PE (8),SPRD (6),Alexa Fluor 647 (4),PE,Cy5 (3),PerCP (3),Alexa Fluor 488 (2),Alexa Fluor 555 (2),Allophycocyanin (2),Cy3 (2),Cy5 (2),Cy5.5 (2),Cy7 (2),Cy7,PE (2),DyLight 488 (2),DyLight 550 (2),DyLight 650 (2),HRP (2),PE-Cy5 (2),PE-DyLight 594 (2),Alexa Fluor 700 (1),PE,DY590 (1),PE,DY647 (1),PE-Dyomics 590 (1),PE-Dyomics 647 (1),PerCP-Cy5.5 (1)
應用范圍
其他選擇 Flow Cytometry (FACS), Immunohistochemistry (IHC)
Flow Cytometry (FACS)(281),Immunohistochemistry (IHC) (77),Western Blotting (WB) (70),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (67),Immunohistochemistry (Frozen Sections) (IHC (fro)) (54),Immunoprecipitation (IP) (49),ELISA (38),Immunofluorescence (IF) (22),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (18),Immunocytochemistry (ICC) (5),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (5),Functional Studies (Func) (4),Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (4),Enzyme Immunoassay (EIA) (2)
[Pubmed] 3 references available
規(guī)格 0.5 mg
發(fā)貨至 中國 (Change)
發(fā)貨時間 23至28個工作日

CD38 抗體

產(chǎn)品細節(jié)

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克隆位點 NIMR-5
亞型 IgG2a
產(chǎn)品特性 The antibody detects: CD38, Mr 42-46 kDa

目標詳細情況

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目標詳細情況

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背景 Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells, and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCR+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages. Monoclonal antibodies to CD38 have been shown to induce B- and T-cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis.
研究領域 CD Antigens, Surface Receptors of Immune Cells

使用細節(jié)

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使用細節(jié)

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應用備注 Working Dilution:
FACS: 1 µg/10^6 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
說明

Induction of B lymphocyte proliferation

樣本量 1 mL
限制 For Research Use only

貯存及處理

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貯存及處理

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緩沖液 Product is supplied as 0.5 mg in 1.0 mL of PBS / NaN3.
儲存液 Sodium azide
注意事項 WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediay. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
注意事項 Protect conjugated products from light.
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儲存條件 4 °C