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Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK)

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Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (N-Term) 抗體的概念:
Z初有人用電泳證明血清中抗體活性在γ球蛋白部分,故曾把抗體統(tǒng)稱為丙種(γ)球蛋白。后來發(fā)現(xiàn),抗體并不都在γ區(qū);并且位于γ區(qū)的球蛋白,也不一定都具有抗體活性,規(guī)格:0.1ml/100µg、0.2ml/200µg

Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (N-Term) 抗體

抗原
Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK)
別名 hnrpk, MGC75642, HNRPK, HNRNPK, CSBP, TUNP, Csbp, Hnrpk, wu:fb37h02, wu:fi34c04, zgc:66162, KBBP, NOVA
抗原表位
 其他選擇N-Term
適用
 其他選擇Rabbit, Murine, Rat ((Rattus)), Dog (Canine), Xenopus laevis, Bovine, Zebrafish (Danio rerio), Human, Chicken
宿主
 其他選擇Rabbit
克隆類型
多克隆
標(biāo)記
 其他選擇非結(jié)合性
應(yīng)用范圍
 其他選擇Immunohistochemistry (IHC), Western Blotting (WB)
[Pubmed] 1 reference available
規(guī)格 50 μg
發(fā)貨至 中國 (更改)
發(fā)貨時間 9至12個工作日

Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (N-Term) 抗體

產(chǎn)品細(xì)節(jié)

引用圖像貯存及處理使用細(xì)節(jié)目標(biāo)詳細(xì)情況回頁首
免疫原 Synthetic peptide directed towards the N terminal of human HNRPK
序列 NTETNGEFGK RPAEDMEEEQ AFKRSRNTDE MVELRILLQS KNAGAVIGKG
預(yù)測反應(yīng) African clawed frog : 100 %, Bovine : 100 %, Chicken : 100 %, Human : 100 %, Mouse : 100 %, Rabbit : 100 %, Rat : 100 %, Zebrafish : 90 %
產(chǎn)品特性 This is a rabbit polyclonal antibody against HNRPK. It was validated on Western Blot and immunohistochemistry.
純化方法 Affinity Purified

Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (N-Term) 抗體目標(biāo)詳細(xì)情況

引用圖像貯存及處理使用細(xì)節(jié)回頁首
別名 HNRPK
背景 HNRPK belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). The hnRNP proteins have distinct nucleic acid binding properties. HNRPK is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference, it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Multiple alternatively spliced transcript variants have been described for this gene but only three variants have been fully described.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference, it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Multiple alternatively spliced transcript variants have been described for this gene but only three variants have been fully described.
分子量 51 kDa
基因ID 3190
NCBI Accession NP_112552, NM_031262
UniProt P61978
研究領(lǐng)域 DNA/RNA, Signaling

Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (N-Term) 抗體使用細(xì)節(jié)

引用圖像貯存及處理目標(biāo)詳細(xì)情況回頁首
應(yīng)用備注 Optimal working dilutions should be determined experimentally by the investigator.
說明

Antigen size: 463 AA

限制 For Research Use only

貯存及處理

引用圖像使用細(xì)節(jié)目標(biāo)詳細(xì)情況回頁首
狀態(tài) Lyophilized
溶解方式 Add 50 µL of distilled water.
濃度 1 mg/mL
緩沖液 PBS buffer with 2 % sucrose
注意事項(xiàng) Avoid repeated freeze-thaw cycles.
儲存條件 -20 °C
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