AlkB, Alkylation Repair Homolog 2 （ALKBH2） （C-Term 返回列表頁

AlkB, Alkylation Repair Homolog 2 (ALKBH2) (C-Term) 抗體

抗原
AlkB, Alkylation Repair Homolog 2 (ALKBH2)
別名 si:dkey-65b12.2, ABH2, 9530023G02, AU016977, Abh2, mABH2, RGD1306377
抗原表位
其他選擇 C-Term
C-Term(9),Internal Region (1),Middle Region (1)
適用
其他選擇 Human, Murine, Rat ((Rattus))
Human(18),Murine (12),Rat ((Rattus)) (12),Bovine (1),Dog (Canine) (1),Zebrafish (Danio rerio) (1)
宿主
其他選擇 Rabbit
Rabbit(15),Mouse (3)
克隆類型
多克隆
應(yīng)用范圍
其他選擇 ELISA, Western Blotting (WB)
Western Blotting (WB)(18),ELISA (11),Immunohistochemistry (IHC) (7),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3),Enzyme Immunoassay (EIA) (2),Immunoassay (IA) (1),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (1)
規(guī)格 0.1 mg
發(fā)貨至 中國(guó) (更改)
發(fā)貨時(shí)間 24至29個(gè)工作日

AlkB, Alkylation Repair Homolog 2 (ALKBH2) (C-Term) 抗體

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免疫原 The immunogen for anti-ALKBH2 antibody: antibody was raised against a 15 amino acid peptide near the carboxy terminus of human ALKBH2.
預(yù)測(cè)反應(yīng) Human Mouse Rat
產(chǎn)品特性 The E. Coli Alkb Protein Protects Against The Cytotoxicity Of Methylating Agents By Repair Of The Specific Dna Lesions Generated In Single-Stranded Dna, Alkbh2 And Alkbh3 Are Mammalian Homologs Of Alkb That Catalyze The Removal Of 1-Methyladenine And 3-Methylcytosine, Modifications That Left Unchecked Could Lead To Cancerous Cells. Mutations In Both Alkbh2 And Alkbh3 Have Been Observed In Pediatric Brain Tumors Indicating That These Proteins Are Important In The Prevention Of Cancer Formation. Like The Histone Demethylase Jmjd1a, Alkbh2 Is A Non-Heme Iron Enzyme That Is Inhibited By Nickel Ions, Suggesting That Inhibition Of Alkbh2 By Nickel Ions May Play A Role In The Development Of Cancer. Conversely, Alkbh2 Mrna And Protein Levels Are Increased Glioma Cells Following Photofrin-Mediated Photodynamic Therapy, An Adjuvant Therapy In Cancer Treatment, Suggesting That Down-Regulating Alkbh2 Expression In Cancer Cells May Enhance The Anti-Cancer Effectiveness Of This Treatment.
純化方法 Affinity chromatography purified via peptide column

AlkB, Alkylation Repair Homolog 2 (ALKBH2) (C-Term) 抗體目標(biāo)詳細(xì)情況

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別名 ALKBH2
背景 Alpha-Ketoglutarate-Dependent Dioxygenase Alkb Homolog2

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AlkB, Alkylation Repair Homolog 2 (ALKBH2) (C-Term) 抗體使用細(xì)節(jié)

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應(yīng)用備注 ALKBH2 antibody can be used for detection of ALKBH2 by Western blot at 1 - 2?μg/mL
限制 For Research Use only

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注意事項(xiàng) As with all antibodies care should be taken to avoid repeated freeze thaw cycles.
Antibodies should not be exposed to prolonged high temperatures.
儲(chǔ)存條件 4 °C
儲(chǔ)存方法 ALKBH2 antibody can be stored at 4 °C
有效期 12 months

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