APP 抗體 返回列表頁

APP 抗體

抗原
Amyloid beta (A4) Precursor Protein (APP)
別名
APP, APP-like, APPL, Abeta, BcDNA:GH04413, CG7727, DmelCG7727, EG:65F1.5, appl, aaa, abeta, abpp, ad1, appi, ctfgamma, cvap, pn2, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, Abpp, Adap, ... show more
APP, APP-like, APPL, Abeta, BcDNA:GH04413, CG7727, DmelCG7727, EG:65F1.5, appl, aaa, abeta, abpp, ad1, appi, ctfgamma, cvap, pn2, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, Abpp, Adap, Ag, Cvap, E030013M08Rik, betaApp, app, wu:fj34d10, wu:fk65e12, zgc:85740 show less
抗原表位
其他選擇 AA 666-670
C-Term(105),N-Term (93),pThr668 (33),pThr743 (33),pSer730 (26),pSer198 (13),pTyr757 (13),AA 18-289 (11),Transcript Variant 1 (10),AA 44-63 (9),Tyr756 (9),AA 737-751 (8),AA 332-362 (7),AA 681-695 (7),Ser730 (7),Thr668 (7),AA 292-312 (6),AA 339-348 (6),Middle Region (6),AA 18-32 (4),AA 666-670 (4),AA 1-14 (3),AA 1-17 (3),AA 32-40 (3),AA 653-662 (3),AA 747-761 (3),Internal Region (3),Thr743 (3),AA 1-40 (2),AA 18-286 (2),AA 18-38 (2),AA 19-305 (2),AA 29-61 (2),AA 333-362 (2),AA 400-450 (2),AA 660-669 (2),AA 671-685 (2),AA 735-763 (2),AA 736-770 (2),Center (2),Soluble (2),AA 1-16 (1),AA 1-245 (1),AA 1-42 (1),AA 17-23 (1),AA 17-42 (1),AA 18-336 (1),AA 23-29 (1),AA 35-40 (1),AA 35-42 (1),AA 350-450 (1),AA 37-42 (1),AA 489-770 (1),AA 50-150 (1),AA 602-757 (1),AA 602-770 (1),AA 643-695 (1),AA 672-711 (1),AA 672-770 (1),Extracellular Domain (1),Glu11 (1),Glu3 (1),Leu310 (1),Thr435 (1),Wild Type (1),pTyr756 (1),pan (1),phosphorylated (1),pyroGlu11 (1)
適用
其他選擇 Human, Murine, Rat ((Rattus))
Human(713),Rat ((Rattus)) (322),Murine (288),Bovine (176),Dog (Canine) (168),Pig (Porcine) (161),Chicken (153),Rabbit (50),Guinea Pig (13),Monkey (13),Frog (4),Non Human Primates (2),Zebrafish (Danio rerio) (2),Horse (Equine) (1),Mammalian (1),Primate (1),Xenopus laevis (1)
宿主
其他選擇 Rabbit
Rabbit(510),Mouse (194),Goat (38),Chicken (6),Sheep (2)
克隆類型
多克隆
標記
其他選擇 非結合性
Biotin(28),FITC (25),HRP (23),Alexa Fluor 350 (15),Alexa Fluor 488 (15),Alexa Fluor 555 (15),Alexa Fluor 647 (15),Cy3 (15),Cy5 (15),Cy5.5 (15),Cy7 (15),PE (7),APC (5),Alkaline Phosphatase (AP) (5),Magnetic Particles (2),Sepharose (2)
應用范圍
其他選擇 Immunofluorescence (IF), Western Blotting (WB)
Western Blotting (WB)(516),ELISA (245),Immunohistochemistry (IHC) (192),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (164),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (149),Immunofluorescence (IF) (71),Flow Cytometry (FACS) (68),Immunoprecipitation (IP) (47),Immunocytochemistry (ICC) (31),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (28),Immunohistochemistry (Frozen Sections) (IHC (fro)) (24),Enzyme Immunoassay (EIA) (17),Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (8),Dot Blot (DB) (7),Immunohistochemistry (Acetone-fixed) (IHC (af)) (2),Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2),Radioimmunoassay (RIA) (2),Proximity Ligation Assay (PLA) (1)
[Pubmed] 4 references available
規(guī)格 50 μg
發(fā)貨至 中國 (更改)
發(fā)貨時間 29至35個工作日

APP 抗體

產品細節(jié)

引用 圖像 貯存及處理 使用細節(jié) 目標詳細情況 回頁首

產品細節(jié)

顯示 隱藏
免疫原 peptide Sequence around amino acids 666~670 (A-V-T-P-E) derived from Human APP protein.
特異性 This antibody detects endogenous levels of total APP protein.
純化方法 Affinity Chromatography using epitope-specific immunogen.

目標詳細情況

引用 圖像 貯存及處理 使用細節(jié) 回頁首

目標詳細情況

顯示 隱藏
別名 Amyloid beta A4 Protein / APP
背景 Amyloid beta precursor protein gene (ABPP) encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Multiple transcript variants encoding several different isoforms have been found for this gene. Isoform APP695 is the predominant form in neuronal tissue, isoform APP751 and isoform APP770 are widely expressed in nonneuronal cells. Isoform APP751 is the most abundant form in T lymphocytes. ABPP is expressed in all fetal tissues examined with the highest levels in brain, kidney, heart and spleen with weak expression observed in liver, ABPP is induced during neuronal differentiation. In the adult brain, highest expression of ABPP gene is found in the frontal lobe of the cortex and in the anterior perisylvian cortex opercular gyri, moderate expression in the cerebellar cortex, the posterior perisylvian cortex opercular gyri and the temporal associated cortex. Weak expression is found in the striate, extra striate and motor cortices. Mutations in ABPP have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).Synonyms: ABPP, APPI, Alzheimer disease amyloid protein, Amyloid Precursor Protein, CVAP, Cerebral vascular amyloid peptide, PreA4, Protease nexin-II
基因ID 351
NCBI Accession NP_000475
UniProt P05067
研究領域 Neurology, Alzheimer's Disease

使用細節(jié)

引用 圖像 貯存及處理 目標詳細情況 回頁首

使用細節(jié)

顯示 隱藏
應用備注 Western Blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 For Research Use only

貯存及處理

引用 圖像 使用細節(jié) 目標詳細情況 回頁首

貯存及處理

顯示 隱藏
濃度 1.0 mg/mL
緩沖液 PBS (without Mg2+ and Ca2+),?pH 7.4 containing 150?mM NaCl, 0.02?% Sodium Azide and 50?% Glycerol.
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事項 Avoid repeated freezing and thawing.
儲存條件 -20 °C
儲存方法 Store the antibody (in aliquots) at -20 °C.

xy-11829R Cortexin 1皮質素1抗體
xy-9666R C8orf708號染色體開放閱讀框70抗體
xy-6478R Carboxypeptidase H胰羧肽酶E抗體
xy-5405R phospho-CK18(Ser60)磷酸化細胞角蛋白18抗體
xy-9693R C20orf11220號染色體開放閱讀框112抗體
xy-9771R C10orf8810號染色體開放閱讀框88抗體
xy-9956R CRCT1富含半胱氨酸C端蛋白1抗體
xy-9957R CREG2E1A激活基因刺激蛋白2抗體
xy-9959R CWH43細胞壁合成蛋白43抗體
xy-9960R C19orf2919號染色體開放閱讀框29抗體
xy-5274R phospho-CDKN1A (Ser130)磷酸化p21蛋白抗體
xy-5275R Phospho-CHK2 (Thr387)磷酸化細胞周期檢測點激酶2抗體
xy-5276R phospho-CaMK2 alpha (Thr305)磷酸化鈣/鈣調素依賴蛋白激酶2α抗體
xy-5277R Phospho-CDK2 (Thr14)磷酸化周期素依賴性激酶2抗體
xy-5278R phospho-CHEK1 (Ser345)磷酸化細胞周期檢測點激酶1抗體
xy-5279R phospho-CDKN1B (Thr198)磷酸化P27抗體/周期素依賴激酶抑制劑抗體
xy-5280R phospho-CTNNA1 (Ser641)磷酸化α-連環(huán)蛋白抗體
xy-5281R Cyclin E2周期素E2抗體
xy-5282R phospho-CaMK2 beta gamma delta (Thr287)磷酸化鈣/鈣調素依賴蛋白激酶CAMK2B/D/G抗體
xy-4097R CASC3腫瘤易感候選基因3抗體
xy-5283R phospho-CASC3(Tyr181)磷酸化腫瘤易感候選基因3抗體
xy-5269R phospho-CREB-1(Ser142)磷酸化CREB-1抗體
xy-5270R phospho-CREB-1(Ser121)磷酸化CREB-1抗體
xy-5287R phospho-CDK6 (Tyr24)磷酸化周期素依賴性激酶6抗體
xy-5147R CBL2原癌基因CBL2抗體
xy-4071R phospho-CBL2 (Tyr674)磷酸化原癌基因CBL2抗體
xy-4095R CTNNBIP1β鏈接素相互作用蛋白1抗體
xy-5266R phospho-CTNNBIP1 (Thr43+Ser50)磷酸化β鏈接素相互作用蛋白1抗體
xy-4074R phospho-Beta catenin (Tyr86) 磷酸化β 連環(huán)素蛋白抗體