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PRL抗體

參   考   價: 1800

訂  貨  量: ≥1 

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更新時間:2017-12-25 21:26:12瀏覽次數(shù):333次

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PRL抗體的概念:
Z初有人用電泳證明血清中抗體活性在γ球蛋白部分,故曾把抗體統(tǒng)稱為丙種(γ)球蛋白。后來發(fā)現(xiàn),抗體并不都在γ區(qū);并且位于γ區(qū)的球蛋白,也不一定都具有抗體活性,規(guī)格:0.1ml/100µg、0.2ml/200µg

PRL抗體

抗原
Prolactin (PRL)
別名 PRL, prolactin, PRLB, PRLSD1, Prl1a1, Prol, RATPRLSD1, RNPROL, AV290867, prl
抗原表位
其他選擇 C-Term
pSer163(23),Ser163 (13),C-Term (12),AA 187-216 (8),AA 47-76 (8),AA 194-223 (7),Ser207 (6),Transcript Variant 1 (6),AA 188-216 (4),AA 29-227 (4),Internal Region (3),AA 1-227 (2),AA 141-171 (2),AA 48-76 (2),N-Term (2),pSer207 (2),AA 1-213 (1),AA 1-226 (1),AA 149-178 (1),AA 29-151 (1),AA 29-228 (1),AA 3-63 (1),AA 30-226 (1),AA 32-228 (1),AA 33-227 (1),Center (1),Domain C (1),Middle Region (1)
適用
其他選擇 Human, Murine, Rat ((Rattus))
Human(302),Murine (34),Rat ((Rattus)) (34),Pig (Porcine) (24),Chicken (12),Sheep (Ovine) (12),Bovine (2),Cat (1),Dog (Canine) (1),Mammalian (1),Squirrel (1)
宿主
其他選擇 Rabbit
Mouse(173),Rabbit (155),Goat (7),Guinea Pig (1),Human (1),Rat (1),Sheep (1)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
HRP(23),Biotin (13),FITC (12),APC (6),Alkaline Phosphatase (AP) (6),PE (6),Alexa Fluor 350 (2),Alexa Fluor 488 (2),Alexa Fluor 555 (2),Alexa Fluor 647 (2),Cy3 (2),Cy5 (2),Cy5.5 (2),Cy7 (2)
應(yīng)用范圍
其他選擇 Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Western Blotting (WB)
ELISA(147),Western Blotting (WB) (134),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (49),Immunohistochemistry (IHC) (34),Enzyme Immunoassay (EIA) (28),Immunohistochemistry (Frozen Sections) (IHC (fro)) (28),Immunofluorescence (IF) (25),Flow Cytometry (FACS) (22),Dot Blot (DB) (20),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (20),Radioimmunoassay (RIA) (20),Immunocytochemistry (ICC) (10),Immunofluorescence (Cultured Cells) (IF (cc)) (10),Protein Assay (PrA) (8),ELISA (Capture) (5),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (5),ELISA (Detection) (3),Immunoassay (IA) (2),Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2),Immunohistochemistry (Paraformaldehyde) (IHC (pfa)) (1),Neutralization (Neut) (1)
規(guī)格 0.1 mg
發(fā)貨至 中國 (更改)
發(fā)貨時間 29至35個工作日

PRL抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

顯示 隱藏
免疫原 Synthetic peptide corresponding to C-terminal of Human Prolactin.
亞型 IgG
特異性 Recognizes Prolactin (C-term). The Anti-Prolactin antibodies have been fully characterized for cross reactivity with other species Prolactin molecules and for other cellular proteins using Western blot analyses.
交叉反應(yīng) (詳細(xì)) Species reactivity (tested):Human, Mouse and Rat.
純化方法 Affinity Chromatography on immobilized antigen

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 Prolactin / PRL
背景 Prolactin is synthesis starts in first few weeks of gestation in pituitary lactotropes and serum levels decline shortly after birth. Prolactin levels rise significantly during pregnancy. Other factors that regulate Prolactin levels include sleep, stress, hypoglycemia and exercise. Prolactin is structurally related to growth hormone and placental lactogen. The genes for these hormone share common structural homology, prolactin is coded by a single gene located on human chromosome 6. The prolactin s a single polypeptide of 199 amino acids with a molecular mass of 23?kDa and has 2 disulfide bond, one more than GH. Majority of Prolactin is in circulation in monomeric form (23?kDa). Unlike GH, the prolactin is glycosylated at asparagine. Some dimeric, polymeric and degraded form of prolactin is also detectable in circulation, but their physiological significance is not known. Prolactin binds to two prolactin receptors, with downstream signal transduction mediated by tyrosine kinase cascade. Physiological effects include breast development, and effects on hypothalamus-pituitary-gonadal axis. Prolactin receptor are also present in T lymphocytes, and prolactin has been shown to modulate immune responses (1). Prolactin secreting tumors are common cause of hyperprolactinemia, in women the symptoms relate to galactorrhea, amenorrhea and infertility. In men the symptoms include galactorrhea, infertility and impotance.
基因ID 5617
NCBI Accession NP_000939
UniProt P01236

使用細(xì)節(jié)

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使用細(xì)節(jié)

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應(yīng)用備注 This antibody is ideal for ELISA and Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 For Research Use only

貯存及處理

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貯存及處理

顯示 隱藏
濃度 0.68 mg/mL
緩沖液 Stabilization buffer with 0.02?% Sodium Azide as preservative
儲存液 Sodium azide
注意事項(xiàng) This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事項(xiàng) Avoid repeated freezing and thawing.
儲存條件 -20 °C
儲存方法 Store the antibody undiluted (in aliquots) at-20 °C.

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