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S100B抗體

抗原
S100 Calcium Binding Protein B (S100B)
別名 AI266795, S100, S100a, NEF, S100-B, S100beta, S100P, AI850290, Bpb
抗原表位
其他選擇 C-Term
AA 1-92(13),C-Term (7),AA 27-56 (5),N-Term (4),Internal Region (3),pSer100 (3),AA 28-56 (2),Center (1),Middle Region (1),full length (1)
適用
其他選擇 Human, Rat ((Rattus))
Human(129),Rat ((Rattus)) (43),Bovine (42),Murine (38),Chicken (13),Rabbit (9),Cat (4),Pig (Porcine) (4)
宿主
其他選擇 Rabbit
Rabbit(96),Mouse (59),Guinea Pig (4),Sheep (4),Goat (2)
克隆類型
多克隆
標記
其他選擇 非結合性
Biotin(8),FITC (7),HRP (4),APC (2),Alkaline Phosphatase (AP) (2),PE (2),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),Magnetic Particles (1),Sepharose (1)
應用范圍
其他選擇 Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
Western Blotting (WB)(116),ELISA (74),Immunohistochemistry (IHC) (53),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (47),Immunohistochemistry (Frozen Sections) (IHC (fro)) (16),Flow Cytometry (FACS) (15),Immunocytochemistry (ICC) (15),Immunoprecipitation (IP) (14),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (10),Immunofluorescence (IF) (8),Dot Blot (DB) (5),Enzyme Immunoassay (EIA) (3),Immunoassay (IA) (2),Purification (Purif) (1),Radioimmunoassay (RIA) (1)
[Pubmed] 2 references available
規(guī)格 0.1 mg
發(fā)貨至 中國 (更改)
發(fā)貨時間 29至35個工作日

S100B抗體

產品細節(jié)

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產品細節(jié)

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免疫原 Purified S100 protein
亞型 IgG
特異性 This antibody detects S100 (alpha/beta) at C-term.
交叉反應 （詳細） Species reactivity (tested):Human, rat
純化方法 Affinity chromatography

目標詳細情況

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別名 S100B
背景 Despite the abundance of calcium in the body, only a fraction of (1?% ) is present in the ionic form in biological fluids and rest is bound to various calcium biding proteins such as calmodulin, S100, calretinin, calbindin, parvalbumins etc. The ionic concentration of calcium is regulated by calcium sensing receptors. These receptors activate trans-cellular transport of calcium across the apical membranes facilitated by a group of low molecular weight calcium binding proteins. The active transport of calcium is achieved by Sodium calcium exchanges and by calcium transport proteins. S100 protein is a member of low MW calcium binding protein family, has two subunits (alfa and beta) and is expressed in S100ab or S100 bb confirmations. Human S100b subunit is a 94 amino acid protein expressed in brain. There are 9 genes (S100A1 through S100A9) that are mapped on chromosome 21q22.2-q22.3. S100 proteins improve contractility of the heart muscle by various mechanisms involving handling of sarcoplasmic reticulum calcium by myofbirilar calcium ion responsiveness. Because of the predominant location of S100 proteins in the glial cells, the S100 protein is leaked in to extracellular matrix and in to the cerebrospinal fluid (CSF) upon CNS injury. The S100 protein is a reliable marker for measuring the extent of CNS and neuronal damage (1, 2). Measurement of S100 protein is also a useful tool in diagnosis of acute stroke (3) and in various brain haemorrhages due to ruptured aneurysm (4).Synonyms: 100 Calcium-binding protein A, 100 Calcium-binding protein B, S-100-A, S-100A, S-100B, S100 alpha, S100 beta, S100-B, S100B
基因ID 6285
NCBI Accession NP_006263
UniProt P04271

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應用備注 Immunohistochemistry on frozen sections. Western blot. Immunoprecipitation.
限制 For Research Use only

貯存及處理

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貯存及處理

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濃度 0.6 - 0.75 mg/mL
緩沖液 Antibody stabilization buffer containing preservatives
注意事項 Avoid repeated freezing and thawing.
儲存條件 -20 °C
儲存方法 Store (in aliquots) at -20 °C.

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