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TP53I3抗體

抗原
Tumor Protein P53 Inducible Protein 3 (TP53I3)
別名 MGC82892, MGC146409, PIG3
適用
其他選擇 Human
Human(51)
宿主
其他選擇 Rabbit
Rabbit(38),Mouse (13)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
Biotin(2),FITC (2),HRP (2),APC (1),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Alkaline Phosphatase (AP) (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),PE (1)
應(yīng)用范圍
其他選擇 Western Blotting (WB)
Western Blotting (WB)(41),ELISA (14),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunoassay (IA) (5),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5),Enzyme Immunoassay (EIA) (2),Immunocytochemistry (ICC) (2),Immunoprecipitation (IP) (2),Immunofluorescence (IF) (1),Immunohistochemistry (IHC) (1)
規(guī)格 0.1 mg
發(fā)貨至 中國 (更改)
發(fā)貨時間 29至35個工作日

TP53I3抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

顯示 隱藏
特異性 This antibody detects endogenous levels of PIG3 protein. (region surrounding Leu265)
交叉反應(yīng) （詳細(xì)） Species reactivity (tested):Human.
純化方法 The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
純度 > 95 % pure by SDS-PAGE

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 TP53I3
背景 The PIG (p53-induced gene) gene family encodes redox-controlling proteins that are involved in p53 tumor suppressor activity. One member of the PIG gene family, p53-inducible gene 3 (PIG3), is a p53 responsive gene that maps, in humans, to chromosome 2p and encodes a protein with significant homology to oxidoreductases. Oxidoreductases are enzymes involved in cellular responses to oxidative stress and irradiation, and they influence the involvement of PIG3 in the metabolism of reactive oxygen species. PIG3 is localized to the cytoplasm and induced in primary, non-transformed, and transformed cell cultures after exposure to genotoxic agents. The induction of PIG3 is p53 dependent and occurs with delayed kinetics as compared with other p53 downstream targets. PIG3 may act with caspase-8 as a key regulatory element in p53-dependent transcriptional deregulation by triggering the caspase cascade and mitochondrial breakdown. PIG3 is highly up-regulated by p53 and may be useful for detecting transient activation of p53.Synonyms: PIG3, Quinone oxidoreductase PIG3, Tumor protein p53-inducible protein 3, p53-induced gene 3 protein
分子量 approx. 36 kDa
基因ID 9540
NCBI Accession NP_001193731
UniProt Q53FA7

使用細(xì)節(jié)

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使用細(xì)節(jié)

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應(yīng)用備注 ELISA: 1: 1000approx. 1: 5000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 For Research Use only

貯存及處理

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貯存及處理

顯示 隱藏
濃度 1,0 mg/mL
緩沖液 Phosphate buffered saline (PBS),?pH 7.2., 0.05?% sodium azide
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事項 DO NOT FREEZE!
儲存條件 4 °C
儲存方法 Store the antibody undiluted at 2-8 °C.xy-2883R EDG6內(nèi)皮細(xì)胞的分化蛋白6抗體
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