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AKT1抗體

抗原
V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)
別名
AKT, AKT1, pkb, xAct, v-akt, v-akt1, akt-1, AKT/PKB, Akt, Akt/PKB, Akt1, PKB, CG4006, D-Akt, DAKT1, DAKT1/PKB, DAkt, DAkt1, DPKB, DRAC-PK, DRAC-PK66, DRAC-PK85, Dakt, Dakt1, DmelCG4006, Dpkb, PKB/AK ... show more
AKT, AKT1, pkb, xAct, v-akt, v-akt1, akt-1, AKT/PKB, Akt, Akt/PKB, Akt1, PKB, CG4006, D-Akt, DAKT1, DAKT1/PKB, DAkt, DAkt1, DPKB, DRAC-PK, DRAC-PK66, DRAC-PK85, Dakt, Dakt1, DmelCG4006, Dpkb, PKB/AKT, PKB/Akt, PKB/dAKT, RAC, RacPK, akt, akt1, dAKT, dAKT/dPKB, dAKT1, dAkt, dAkt/PKB, dAkt1, dPKB, dakt, dakt1, l(3)04226, l(3)89Bq, p-Akt, pAkt, ATAKT1, F18A8.2, F18A8_2, K+ transporter 1, POTASSIUM TRANSPORTER, Rac, PKBalpha, CWS6, PKB-ALPHA, PRKBA, RAC-ALPHA show less
抗原表位
其他選擇 pThr308
pSer473(125),C-Term (76),pThr308 (76),Internal Region (63),N-Term (58),pThr450 (58),pTyr326 (34),pSer129 (33),Thr308 (30),pTyr474 (29),Ser473 (26),Ser129 (17),pSer246 (17),Tyr326 (16),Thr450 (15),pThr34 (13),pSer124 (11),AA 1-480 (9),AA 289-318 (8),AA 21-49 (7),AA 461-477 (7),AA 460-480 (5),Ser124 (5),pThr72 (5),AA 448-452 (4),Tyr312 (4),Tyr315 (4),Tyr316 (4),AA 1-481 (3),AA 115-144 (3),AA 282-309 (3),AA 302-311 (3),AA 306-310 (3),AA 381-480 (3),AA 428-457 (3),AA 438-468 (3),AA 471-475 (3),pTyr315 (3),AA 1-149 (2),AA 22-49 (2),AA 25-75 (2),AA 465-479 (2),AA 49-76 (2),Asp302 (2),Ser13 (2),Ser133 (2),Tyr1586 (2),pSer472 (2),pSer474 (2),pThr326 (2),pTyr312 (2),pTyr316 (2),phosphorylated (2),phosphospecific (2),AA 1-177 (1),AA 1-259 (1),AA 106-122 (1),AA 107-122 (1),AA 107-135 (1),AA 11-60 (1),AA 122-443 (1),AA 127-200 (1),AA 2-480 (1),AA 212-261 (1),AA 216-480 (1),AA 274-323 (1),AA 276-325 (1),AA 292-341 (1),AA 302-314 (1),AA 375-479 (1),AA 38-87 (1),AA 416-465 (1),AA 431-480 (1),AA 446-475 (1),AA 464-477 (1),AA 466-480 (1),AA 5-30 (1),AA 56-85 (1),AA 74-89 (1),AA 80 (1),AA 85-100 (1),AA 90-139 (1),AA 95-144 (1),Ala444 (1),Arg69 (1),Glu242 (1),Glu40 (1),Leu321 (1),Met118 (1),Middle Region (1),Pro125 (1),Pro240 (1),Pro467 (1),Pro470 (1),Ser119 (1),Ser1303 (1),Ser131 (1),Ser134 (1),Ser136 (1),Ser137 (1),Ser190 (1),Ser246 (1),Thr34 (1),Thr72 (1),Tyr434 (1),Tyr437 (1),Tyr473 (1),full length (1),pTyr434 (1),pTyr437 (1),pTyr473 (1)
適用
其他選擇 Human
Human(994),Murine (553),Rat ((Rattus)) (510),Chicken (117),Dog (Canine) (104),Bovine (83),Pig (Porcine) (65),Monkey (27),Rabbit (14),Chimpanzee (6),Xenopus laevis (3),All Species (1),Arabidopsis thaliana (1),Frog (1),Rat (Meriones) (1)
宿主
其他選擇 Rabbit
Rabbit(842),Mouse (159),Sheep (13),Rat (5),Goat (4),Chicken (3)
克隆類型 (克隆位點(diǎn))
多克隆 (RB27685)
標(biāo)記
其他選擇 非結(jié)合性
Biotin(31),HRP (25),FITC (24),PE (19),APC (14),Alkaline Phosphatase (AP) (13),Alexa Fluor 350 (10),Alexa Fluor 488 (10),Alexa Fluor 555 (10),Alexa Fluor 647 (10),Cy3 (10),Cy5 (10),Cy5.5 (10),Cy7 (10),Agarose Beads (1),Atto 594 (1),CF (1),Magnetic Particles (1),Sepharose (1)
應(yīng)用范圍
其他選擇 Dot Blot (DB), Immunofluorescence (IF)
Western Blotting (WB)(828),ELISA (458),Immunohistochemistry (IHC) (382),Immunofluorescence (IF) (168),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (160),Flow Cytometry (FACS) (107),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (100),Immunoprecipitation (IP) (76),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (54),Immunocytochemistry (ICC) (52),Dot Blot (DB) (44),Enzyme Immunoassay (EIA) (36),Immunohistochemistry (Frozen Sections) (IHC (fro)) (12),Fluorescence Microscopy (FM) (3),Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (3),Proximity Ligation Assay (PLA) (3),Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2),Cell Culture (CC) (1),Fluorescence Resonance Energy Transfer Microscopy (FRET) (1),Immunoassay (IA) (1),RNA Interference (RNAi) (1),Stimulated Emission Depletion Microscopy (STED) (1)
[Pubmed] 1 reference available
規(guī)格 400 μL
發(fā)貨至 中國(guó) (更改)
發(fā)貨時(shí)間 9至13個(gè)工作日

AKT1抗體

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產(chǎn)品細(xì)節(jié)

顯示 隱藏
免疫原 This AKT1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Thr308 of human AKT1.
克隆位點(diǎn) RB27685
亞型 Ig
特異性 This Phospho-AKT1 (Thr308) Antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected surrounding Thr308 of human AKT1.
純化方法 This antibody is purified through a protein A column, followed by peptide affinity purification.

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目標(biāo)詳細(xì)情況

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別名 AKT1
背景 The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by plaet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].
Synonyms: RAC-alpha serine/threonine-protein kinase,AKT1,PKB, RAC
分子量 55686 DA
基因ID 207
NCBI Accession NP_005154
UniProt P31749
研究領(lǐng)域 Translation Factors, Protein Modifications, Signaling, Neurology, Cell Structure, Ubiquitin-related antibodies, Apoptosis/Necrosis, Phospho-specific antibodies, Cell Signaling, Cancer, Chromatin, Metabolism

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應(yīng)用備注 DB = 1:500, IF = 1:10-50
限制 For Research Use only

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貯存及處理

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狀態(tài) Liquid
濃度 0.5 mg/mL
緩沖液 PBS with 0.09 % (W/V) sodium azide
儲(chǔ)存液 Sodium azide
注意事項(xiàng) This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲(chǔ)存條件 4 °C/-20 °C
儲(chǔ)存方法 Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期 6 months

xy-3034R Phospho-ATP1A1 (Tyr10)磷酸化鈉鉀ATP酶蛋白a1抗體
xy-3035R Phospho-ATP1A1 (Ser16)磷酸化鈉鉀ATP酶蛋白a1抗體
xy-2745R Acetyl CoA Carboxylase乙酰輔酶A羧化酶抗體
xy-3036R Phospho-Acetyl Coenzyme A carboxylase alpha (Ser78)磷酸化乙酰輔酶A羧化酶抗體
xy-3038R Phospho-Ack1 (Tyr859 + 860)磷酸化Ack1抗體
xy-3025R phospho-AMPK alpha-1(Ser485+Ser491)磷酸化腺苷單磷酸活化蛋白激酶α1抗體
xy-3026R phospho-AMPK beta 1 (Ser108)磷酸化腺苷單磷酸活化蛋白激酶β1抗體
xy-3022R phospho-ALK (Tyr1604)磷酸化間變型淋巴瘤激酶抗體
xy-2272R phospho-ATM(Ser1981)磷酸化毛細(xì)血管擴(kuò)張性共濟(jì)失調(diào)癥突變蛋白抗體
xy-3037R phospho-ATP citrate lyase (Ser455)磷酸化三磷酸腺檸檬酸裂解酶抗體
xy-3030R phospho-ATR (Ser428)磷酸化ATR抗體
xy-7960R AMN1細(xì)胞核重定位及紡錘體檢查點(diǎn)蛋白AMN1抗體
xy-7957R ALG11天門冬酰胺連接糖基化11抗體
xy-3777R ASF1A細(xì)胞衰老相關(guān)蛋白ASF1A抗體
xy-8457R AGPHD1氨基糖苷類磷酸結(jié)構(gòu)域蛋白抗體
xy-4119R ASGPR1唾液酸糖蛋白受體1抗體
xy-9100R ARSF芳香基硫酸酯酶F抗體
xy-6980R AKAP5A激酶錨定蛋白5抗體
xy-4807R ATXN3L小腦脊髓共濟(jì)失調(diào)蛋白3抗體
xy-9297R ASTE1ASTE1蛋白抗體
xy-5212R phospho-APG4B(Ser309)磷酸化自噬相關(guān)蛋白4B抗體
xy-9790R AFAP微絲相關(guān)蛋白1抗體
xy-4235R ADORA1腺苷A1A受體抗體
xy-4231R ARSB芳基硫酸酯酶B抗體
xy-4234R ABATγ氨基丁酸轉(zhuǎn)氨酶抗體
xy-6513R A2BP1共濟(jì)失調(diào)蛋白2結(jié)合蛋白1抗體