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XBP1抗體

抗原
X-Box Binding Protein 1 (XBP1)
別名 treb5, xXBP1, xbp2, XBP1P1, XBPP1, xbp1, TREB5, XBP-1, XBP2, D11Ertd39e, TREB-5, HTF, cb918, id:ibd1195, trebf, wu:fb02h05, wu:fb63f10, xbp1a, xbp1b
抗原表位
其他選擇 C-Term, AA 217-244
C-Term(24),N-Term (17),AA 123-225 (12),Internal Region (11),AA 224-252 (7),AA 2-160 (5),AA 70-100 (5),AA 1-261 (3),AA 1-74 (2),AA 62-91 (2),AA 130-261 (1),AA 188-287 (1),AA 217-244 (1),AA 35-249 (1),AA 90-261 (1),Center (1)
適用
其他選擇 Murine
Human(124),Murine (58),Rat ((Rattus)) (41),Bovine (15),Pig (Porcine) (15),Chicken (13),Dog (Canine) (4),Xenopus laevis (1),Zebrafish (Danio rerio) (1)
宿主
其他選擇 Rabbit
Rabbit(72),Mouse (47),Goat (7),Chicken (5)
克隆類型 (克隆位點(diǎn))
多克隆 (RB31994)
標(biāo)記
其他選擇 非結(jié)合性
FITC(4),HRP (4),APC (3),Alkaline Phosphatase (AP) (3),PE (3),Biotin (2),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1)
應(yīng)用范圍
其他選擇 Western Blotting (WB)
Western Blotting (WB)(118),ELISA (66),Immunocytochemistry (ICC) (29),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (22),Immunohistochemistry (IHC) (16),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Flow Cytometry (FACS) (9),Immunofluorescence (IF) (9),Enzyme Immunoassay (EIA) (7),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (6),Immunoassay (IA) (3),Dot Blot (DB) (2),Immunoprecipitation (IP) (2),Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
[Pubmed] 1 reference available
規(guī)格 400 μL
發(fā)貨至 中國 (更改)
發(fā)貨時(shí)間 9至13個(gè)工作日

XBP1抗體

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產(chǎn)品細(xì)節(jié)

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免疫原 This XBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-244 AA from the C-terminal region of human XBP1.
克隆位點(diǎn) RB31994
亞型 Ig
特異性 This XBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-252 amino acids from the C-terminal region of human XBP1.
純化方法 This antibody is purified through a protein A column, followed by peptide affinity purification.

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 XBP1
背景 This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor. The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress. A pseudogene of XBP1 has been identified and localized to chromosome 5.
Synonyms: X-box-binding protein 1,XBP1,TREB5, XBP2
分子量 28695 DA
基因ID 7494
NCBI Accession NP_005071, NP_001073007
UniProt P17861
研究領(lǐng)域 Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Cell Structure

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應(yīng)用備注 WB = 1:1000
限制 For Research Use only

貯存及處理

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貯存及處理

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狀態(tài) Liquid
濃度 0.5 mg/mL
緩沖液 PBS with 0.09 % (W/V) sodium azide
儲(chǔ)存液 Sodium azide
注意事項(xiàng) This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲(chǔ)存條件 4 °C/-20 °C
儲(chǔ)存方法 XBP1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
有效期 6 monthsxy-4073R phospho-CPI17 alpha (Thr38) 磷酸化蛋白磷酸激酶PKC/CPI-17抗體
xy-8459R Centromere protein K著絲粒蛋白K
xy-4503R CTAG1B腫瘤/睪丸抗原1B
xy-0988R Transferrin receptor轉(zhuǎn)鐵蛋白受體抗體
xy-15306R C8orfK298號(hào)染色體開放閱讀框K29抗體
xy-2375R CYP3A4細(xì)胞色素P450 3A4抗體
xy-4108R Cytochrome P450 2D1細(xì)胞色素CYP2D1抗體
xy-4884R CD33CD33抗體
xy-6137R CtIP視網(wǎng)膜母細(xì)胞瘤結(jié)合蛋白8抗體
xy-9772R C10orf9310號(hào)染色體開放閱讀框93抗體
xy-9773R C10orf6310號(hào)染色體開放閱讀框63抗體
xy-9774R C10orf13210號(hào)染色體開放閱讀框132抗體
xy-9775R C10orf3010號(hào)染色體開放閱讀框30抗體
xy-9776R C10orf14010號(hào)染色體開放閱讀框140抗體
xy-9777R C1orf1251號(hào)染色體開放閱讀框125抗體
xy-9778R C1orf1291號(hào)染色體開放閱讀框129抗體
xy-9779R C1orf1591號(hào)染色體開放閱讀框159抗體
xy-9780R C1orf1631號(hào)染色體開放閱讀框163抗體
xy-9781R C1orf1721號(hào)染色體開放閱讀框172抗體
xy-9782R C1orf21號(hào)染色體開放閱讀框2抗體
xy-9783R C1orf191號(hào)染色體開放閱讀框19抗體
xy-9784R C1orf251號(hào)染色體開放閱讀框25抗體
xy-9785R C1orf311號(hào)染色體開放閱讀框31抗體
xy-9786R C1orf511號(hào)染色體開放閱讀框51抗體
xy-9787R C1orf521號(hào)染色體開放閱讀框52抗體
xy-9788R C1orf671號(hào)染色體開放閱讀框67抗體