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TLR9抗體

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更新時間:2018-01-04 23:11:39瀏覽次數(shù):451次

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TLR9抗體的概念:
Z初有人用電泳證明血清中抗體活性在γ球蛋白部分,故曾把抗體統(tǒng)稱為丙種(γ)球蛋白。后來發(fā)現(xiàn),抗體并不都在γ區(qū);并且位于γ區(qū)的球蛋白,也不一定都具有抗體活性,規(guī)格:0.1ml/100µg、0.2ml/200µg

TLR9抗體

抗原
Toll-Like Receptor 9 (TLR9)
別名 CD289
抗原表位
其他選擇 C-Term, AA 842-870
C-Term(29),N-Term (16),AA 268-284 (10),AA 841-870 (7),AA 99-215 (7),Internal Region (7),AA 1-815 (6),AA 370-473 (5),Cytoplasmic Domain (4),Middle Region (4),AA 1050-1100 (3),AA 204-224 (3),AA 200-300 (2),AA 205-235 (2),AA 26-300 (2),AA 311-465 (2),Center (2),Extracellular Domain (2),AA 218-314 (1),AA 26-330 (1),AA 424-698 (1),AA 437-455 (1),AA 64-189 (1),AA 842-870 (1),Internal Domain (1),Isoform A (1)
適用
其他選擇 Human
Human(154),Murine (87),Rat ((Rattus)) (36),Pig (Porcine) (16),Dog (Canine) (14),Bovine (13),Monkey (2),Chimpanzee (1),Protozoa (1)
宿主
其他選擇 Rabbit
Rabbit(101),Mouse (51),Rat (25),Goat (7),Chicken (4),Sheep (1)
克隆類型 (克隆位點)
多克隆 (RB33688)
標(biāo)記
其他選擇 非結(jié)合性
Biotin(19),FITC (13),PE (10),HRP (4),APC (3),Alkaline Phosphatase (AP) (3),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),Pacific Blue (1)
應(yīng)用范圍
其他選擇 Western Blotting (WB), Flow Cytometry (FACS)
Western Blotting (WB)(141),Flow Cytometry (FACS) (80),ELISA (54),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (47),Immunohistochemistry (Frozen Sections) (IHC (fro)) (33),Immunohistochemistry (IHC) (32),Immunocytochemistry (ICC) (17),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (8),Enzyme Immunoassay (EIA) (7),Immunofluorescence (IF) (7),Immunoprecipitation (IP) (3),Functional Studies (Func) (2),Immunoassay (IA) (2),Dot Blot (DB) (1),Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (1)
[Pubmed] 1 reference available
規(guī)格 400 μL
發(fā)貨至 中國 (更改)
發(fā)貨時間 9至13個工作日

TLR9抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

顯示 隱藏
免疫原 This TLR9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 842-870 AA from the C-terminal region of human TLR9.
克隆位點 RB33688
亞型 Ig
特異性 This TLR9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 841-870 amino acids from the C-terminal region of human TLR9.
純化方法 This antibody is purified through a protein A column, followed by peptide affinity purification.

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 TLR9
背景 The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
Synonyms: Toll-like receptor 9,TLR9,
分子量 115860 DA
基因ID 54106
NCBI Accession NP_059138
UniProt Q9NR96
研究領(lǐng)域 Cell Signaling, Cell Structure, Protein Modifications, Chromatin, Signaling

使用細(xì)節(jié)

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使用細(xì)節(jié)

顯示 隱藏
應(yīng)用備注 WB = 1:1000, FACS = 1:10-50
限制 For Research Use only

貯存及處理

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貯存及處理

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狀態(tài) Liquid
濃度 0.31 mg/mL
緩沖液 PBS with 0.09 % (W/V) sodium azide
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲存條件 4 °C/-20 °C
儲存方法 TLR9 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
有效期 6 months

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