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MCM8抗體

抗原
Minichromosome Maintenance Deficient 8 (MCM8)
別名 C20orf154, dJ967N21.5, 5730432L01Rik
抗原表位
其他選擇 N-Term
N-Term(11),AA 321-351 (7),C-Term (5),AA 1-199 (1),AA 1-50 (1),AA 622-818 (1),AA 622-840 (1),AA 646-735 (1)
適用
其他選擇 Murine, Rat ((Rattus)), Bovine, Dog (Canine), Human, Chicken
Human(35),Murine (14),Rat ((Rattus)) (12),Chicken (3),Bovine (3),Dog (Canine) (3),Xenopus laevis (2)
宿主
其他選擇 Rabbit
Rabbit(31),Goat (3),Mouse (1)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
APC(1),Alkaline Phosphatase (AP) (1),Biotin (1),FITC (1),HRP (1),PE (1)
應(yīng)用范圍
其他選擇 Western Blotting (WB)
Western Blotting (WB)(35),ELISA (10),Immunohistochemistry (IHC) (4),Immunoprecipitation (IP) (3)
[Pubmed] 1 reference available
規(guī)格 50 μg
發(fā)貨至 中國 (更改)
發(fā)貨時(shí)間 9至12個(gè)工作日

MCM8抗體

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產(chǎn)品細(xì)節(jié)

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免疫原 Synthetic peptide directed towards the N terminal of human MCM8
序列 ELRDAPEKTL ACMGLAIHQV LTKDLERHAA ELQAQEGLSN DGETMVNVPH
預(yù)測(cè)反應(yīng) Bovine : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rat : 100 %, Chicken : 90 %, Dog : 90 %
產(chǎn)品特性 This is a rabbit polyclonal antibody against MCM8. It was validated on Western Blot using a cell lysate as a positive control.
純化方法 Affinity Purified

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 MCM8
背景 This protein is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.
分子量 94 kDa
基因ID 84515
NCBI Accession NP_115874, NM_032485
UniProt Q9UJA3
研究領(lǐng)域 Chromatin and Nuclear Signaling, Chromatin Binding Proteins, Transcription Factors

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應(yīng)用備注 Optimal working dilutions should be determined experimentally by the investigator.
說明

Antigen size: 840 AA

限制 For Research Use only

貯存及處理

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狀態(tài) Lyophilized
溶解方式 Add 50 µL of distilled water.
濃度 1 mg/mL
緩沖液 PBS buffer with 2 % sucrose
注意事項(xiàng) Avoid repeated freeze-thaw cycles.
儲(chǔ)存條件 -20 °C
儲(chǔ)存方法 For longer periods of storage, store at -20 °C

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