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P4HB抗體 

抗原
Prolyl 4-Hydroxylase, beta Polypeptide (P4HB)
別名 CG6988, DmelCG6988, Dpdi, EP(3)1022, PDI, dpdi, pdi, Pdi, Pdi2, mKIAA0994, DSI, ERBA2L, GIT, P4Hbeta, PDIA1, PHDB, PO4DB, PO4HB, PROHB, ERp59, Pdia1, Thbp, PDIR, p55, PDA2, PDIP, XPDIp
抗原表位
其他選擇 N-Term
AA 1-505(14),C-Term (14),AA 1-506 (4),AA 1-508 (3),AA 100-150 (2),AA 23-227 (2),AA 436-464 (2),AA 443-472 (2),N-Term (2),AA 18-505 (1),AA 212-463 (1),AA 216-465 (1),AA 23-197 (1),AA 269-507 (1),AA 499-509 (1),Pro329 (1)
適用
其他選擇 Rabbit, Murine, Rat ((Rattus)), Bovine, Xenopus laevis, Human, Chicken
Human(92),Murine (45),Rat ((Rattus)) (40),Bovine (21),Chicken (13),Horse (Equine) (8),Monkey (7),Xenopus laevis (7),Hamster (5),Pig (Porcine) (5),Sheep (Ovine) (4),Yeast (4),Dog (Canine) (3),Guinea Pig (3),Mammalian (2),Rabbit (1),Yeast (Pichia pastoris) (1)
宿主
其他選擇 Rabbit
Rabbit(92),Mouse (23)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
HRP(10),FITC (8),Biotin (7),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1)
應(yīng)用范圍
其他選擇 Immunohistochemistry (IHC), Western Blotting (WB)
Western Blotting (WB)(88),ELISA (45),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (31),Immunofluorescence (IF) (24),Immunocytochemistry (ICC) (22),Immunohistochemistry (IHC) (22),Immunoprecipitation (IP) (15),Flow Cytometry (FACS) (13),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunohistochemistry (Frozen Sections) (IHC (fro)) (9),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (4),Immunoassay (IA) (3),Enzyme Immunoassay (EIA) (1),Functional Studies (Func) (1),Immunoelectron Microscopy (IEM) (1),Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (1)
[Pubmed] 1 reference available
規(guī)格 50 μg
發(fā)貨至 中國 (更改)
發(fā)貨時(shí)間 9至12個(gè)工作日

P4HB抗體 

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

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免疫原 Synthetic peptide directed towards the N terminal of human P4HB
序列 TIKFFRNGDT ASPKEYTAGR EADDIVNWLK KRTGPAATTL PDGAAAESLV
預(yù)測反應(yīng) Bovine : 100 %, Human : 100 %, Mouse : 100 %, Dog : 80 %, African clawed frog : 70 %
產(chǎn)品特性 This is a rabbit polyclonal antibody against P4HB. It was validated on Western Blot and immunohistochemistry.
純化方法 Affinity Purified

 目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 P4HB
背景 P4HB is the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.
分子量 55 kDa
基因ID 5034
NCBI Accession NP_000909, NM_000918
UniProt P07237
研究領(lǐng)域 Cancer, Extracellular Matrix

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應(yīng)用備注 Optimal working dilutions should be determined experimentally by the investigator.
說明

Antigen size: 508 AA

限制 For Research Use only

貯存及處理

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貯存及處理

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狀態(tài) Lyophilized
溶解方式 Add 50 µL of distilled water.
濃度 1 mg/mL
緩沖液 PBS buffer with 2 % sucrose
注意事項(xiàng) Avoid repeated freeze-thaw cycles.
儲(chǔ)存條件 -20 °C
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