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PCDHA5抗體
抗原
Protocadherin alpha 5 (PCDHA5)
別名 PCDHA5, CNR6, CNRN6, CNRS6, CRNR6, PCDH-ALPHA5, Cnr6, Crnr6, rCNRv05
抗原表位
其他選擇 N-Term
AA 294-323(8),Internal Region (6),N-Term (4),AA 183-289 (2),AA 183-290 (1),AA 21-246 (1),AA 287-315 (1),Middle Region (1)
適用
其他選擇 Murine, Rat ((Rattus)), Dog (Canine), Bovine, Human
Human(34),Murine (18),Rat ((Rattus)) (18),Bovine (13),Pig (Porcine) (13)
宿主
其他選擇 Rabbit
Rabbit(30),Mouse (4)
克隆類(lèi)型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
Biotin(2),FITC (2),HRP (2),PE (2),APC (1),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Alkaline Phosphatase (AP) (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1)
應(yīng)用范圍
其他選擇 Western Blotting (WB)
Western Blotting (WB)(23),ELISA (12),Flow Cytometry (FACS) (11),Immunohistochemistry (IHC) (11),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4),Enzyme Immunoassay (EIA) (1)
[Pubmed] 1 reference available
規(guī)格 50 μg
發(fā)貨至 中國(guó) (更改)
發(fā)貨時(shí)間 9至12個(gè)工作日

PCDHA5抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

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免疫原 Synthetic peptide directed towards the N terminal of human PCDHA5
序列 VYSRRGSLGS RLLLLWLLLA YWKAGSGQLH YSIPEEAKHG TFVGRIAQDL
預(yù)測(cè)反應(yīng) Mouse : 100 %, Rat : 100 %, Guinea pig : 90 %
產(chǎn)品特性 This is a rabbit polyclonal antibody against PCDHA5. It was validated on Western Blot using a cell lysate as a positive control.
純化方法 Affinity Purified

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 PCDHA5
背景 The gene encoding PCDHA5 is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. PCDHA5 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHA5 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
分子量 99 kDa
基因ID 56143
NCBI Accession NM_018908, NP_061731
UniProt Q9Y5H7
研究領(lǐng)域 Signaling

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應(yīng)用備注 Optimal working dilutions should be determined experimentally by the investigator.
說(shuō)明

Antigen size: 936 AA

限制 For Research Use only

貯存及處理

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狀態(tài) Lyophilized
溶解方式 Add 50 µL of distilled water.
濃度 1 mg/mL
緩沖液 PBS buffer with 2 % sucrose
注意事項(xiàng) Avoid repeated freeze-thaw cycles.
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