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glutathione S-transferase mu 3 brain抗體

抗原
Glutathione S-Transferase mu 3 (Brain) (glutathione S-transferase mu 3 brain)
別名 GstYb4, Gstm4, GST5, GSTB, GSTM3-3, GTM3, Fsc2, mGSTM5
抗原表位
其他選擇 Middle Region
Internal Region(5),AA 1-216 (1),AA 1-225 (1),AA 8-223 (1),Middle Region (1)
適用
其他選擇 Murine, Rat ((Rattus)), Bovine, Dog (Canine), Human
Human(18),Bovine (1),Dog (Canine) (1),Murine (1),Pig (Porcine) (1),Rabbit (1),Rat ((Rattus)) (1),Xenopus laevis (1)
宿主
其他選擇 Rabbit
Rabbit(13),Goat (4),Mouse (1)
克隆類型
多克隆
應用范圍
其他選擇 Western Blotting (WB)
Western Blotting (WB)(15),ELISA (9),Immunohistochemistry (IHC) (5),Immunoassay (IA) (1),Immunocytochemistry (ICC) (1),Immunohistochemistry (Frozen Sections) (IHC (fro)) (1),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1)
[Pubmed] 1 reference available
規(guī)格 50 μg
發(fā)貨至 中國 (更改)
發(fā)貨時間 9至12個工作日

glutathione S-transferase mu 3 brain抗體

產品細節(jié)

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產品細節(jié)

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免疫原 Synthetic peptide directed towards the middle region of human GSTM3
序列 EEKIRVDIIE NQVMDFRTQL IRLCYSSDHE KLKPQYLEEL PGQLKQFSMF
預測反應 Human : 100 %, Pig : 90 %, Rabbit : 80 %, Bovine : 80 %, Dog : 70 %
產品特性 This is a rabbit polyclonal antibody against GSTM3. It was validated on Western Blot using a cell lysate as a positive control.
純化方法 Affinity Purified

目標詳細情況

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目標詳細情況

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別名 GSTM3
背景 Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. GSTM3 is a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins.Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins.
分子量 26 kDa
基因ID 2947
NCBI Accession NP_000840, NM_000849
UniProt P21266
研究領域 Signaling, Metabolism

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應用備注 Optimal working dilutions should be determined experimentally by the investigator.
說明

Antigen size: 225 AA

限制 For Research Use only

貯存及處理

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貯存及處理

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狀態(tài) Lyophilized
溶解方式 Add 50 µL of distilled water.
濃度 1 mg/mL
緩沖液 PBS buffer with 2 % sucrose
注意事項 Avoid repeated freeze-thaw cycles.
儲存條件 -20 °C
儲存方法 For longer periods of storage, store at -20 °C

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