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SNAP23抗體

抗原
Synaptosomal-Associated Protein, 23kDa (SNAP23)
別名 23kDa, AA408749, SNAP-23, Sndt, Syndet, HsT17016, SNAP23A, SNAP23B, XOSNAP-23, snap23-A
抗原表位
其他選擇 N-Term
C-Term(11),AA 1-212 (7),AA 169-199 (7),AA 1-211 (4),Internal Region (4),AA 135-144 (2),AA 86-210 (2),N-Term (2),AA 1-108 (1),AA 1-132 (1),AA 193-210 (1),AA 6-211 (1)
適用
其他選擇 Rabbit, Murine, Rat ((Rattus)), Zebrafish (Danio rerio), Dog (Canine), Bovine, Xenopus laevis, Human, Chicken
Human(68),Rat ((Rattus)) (26),Murine (22),Bovine (14),Pig (Porcine) (12),Dog (Canine) (1),Rabbit (1)
宿主
其他選擇 Rabbit
Rabbit(50),Mouse (11),Goat (8),Guinea Pig (1)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
Biotin(3),FITC (3),HRP (3),APC (2),Alkaline Phosphatase (AP) (2),PE (2),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1)
應(yīng)用范圍
其他選擇 Western Blotting (WB)
Western Blotting (WB)(56),ELISA (33),Immunohistochemistry (IHC) (23),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (16),Immunofluorescence (IF) (11),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunoprecipitation (IP) (6),Enzyme Immunoassay (EIA) (3),Immunocytochemistry (ICC) (3),Immunoassay (IA) (2),Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (1),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (1),Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
[Pubmed] 1 reference available
規(guī)格 50 μg
發(fā)貨至 中國(guó) (更改)
發(fā)貨時(shí)間 9至12個(gè)工作日

SNAP23抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

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免疫原 Synthetic peptide directed towards the N terminal of human SNAP23
序列 GIKTITMLDE QKEQLNRIEE GLDQINKDMR ETEKTLN KCCGLCVCPC
預(yù)測(cè)反應(yīng) Human : 100 %, Chicken : 80 %, Dog : 80 %, Mouse : 80 %, Pig : 80 %, Rabbit : 80 %, African clawed frog : 70 %, Bovine : 70 %
產(chǎn)品特性 This is a rabbit polyclonal antibody against SNAP23. It was validated on Western Blot using a cell lysate as a positive control.
純化方法 Affinity Purified

目標(biāo)詳細(xì)情況

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別名 SNAP23
背景 SNAP23 is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene.Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
分子量 23 kDa
基因ID 8773
NCBI Accession NP_003816, NM_003825
UniProt O00161
研究領(lǐng)域 Neurology

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應(yīng)用備注 Optimal working dilutions should be determined experimentally by the investigator.
說明

Antigen size: 211 AA

限制 For Research Use only

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狀態(tài) Lyophilized
溶解方式 Add 50 µL of distilled water.
濃度 1 mg/mL
緩沖液 PBS buffer with 2 % sucrose
注意事項(xiàng) Avoid repeated freeze-thaw cycles.
儲(chǔ)存條件 -20 °C
儲(chǔ)存方法 For longer periods of storage, store at -20 °C

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