LDLR 抗體 返回列表頁

LDLR 抗體

抗原
Low Density Lipoprotein Receptor (LDLR)
別名 FH, FHC, LDLCQ2, Hlb301, LDLRA, LDLA
抗原表位
其他選擇 AA 1-790
AA 1-788(14),Extracellular Domain (10),AA 1-790 (9),AA 500-550 (8),Internal Region (8),AA 105-205 (4),AA 184-195 (4),AA 391-419 (2),AA 499-511 (2),C-Term (2),Center (2),AA 1-860 (1),AA 105-206 (1),AA 184-196 (1),AA 22-788 (1),AA 228-562 (1),AA 29-205 (1),AA 398-427 (1),AA 810-860 (1),AA 850 (1),N-Term (1)
適用
其他選擇 Murine
Human(95),Murine (40),Bovine (28),Rat ((Rattus)) (20),Dog (Canine) (12),Guinea Pig (12),Pig (Porcine) (12),Monkey (6),Hamster (1),Rabbit (1)
宿主
其他選擇 Rabbit
Rabbit(79),Mouse (27),Chicken (9),Goat (2)
克隆類型 (克隆位點)
單克隆 (32)
標(biāo)記
其他選擇 FITC
Biotin(13),PE (6),FITC (5),HRP (2),APC (1),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Alkaline Phosphatase (AP) (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),DyLight 488 (1),DyLight 550 (1),DyLight 650 (1)
應(yīng)用范圍
其他選擇 Flow Cytometry (FACS)
Western Blotting (WB)(74),ELISA (46),Flow Cytometry (FACS) (42),Immunofluorescence (IF) (11),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunohistochemistry (IHC) (10),Immunocytochemistry (ICC) (9),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9),Immunohistochemistry (Frozen Sections) (IHC (fro)) (7),Immunoprecipitation (IP) (7),Enzyme Immunoassay (EIA) (3),Functional Studies (Func) (2),Immunoassay (IA) (1),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (1),Indirect Immunofluorescence Assay (IFA) (1)
規(guī)格 50 tests
發(fā)貨至 中國 (更改)

LDLR 抗體

產(chǎn)品細節(jié)

圖像 貯存及處理 使用細節(jié) 目標(biāo)詳細情況 回頁首

產(chǎn)品細節(jié)

顯示 隱藏
免疫原 Recombinant Mouse LDLR / LDL Receptor protein
克隆位點 32
亞型 IgG
特異性 Mouse LDLR / LDL Receptor
產(chǎn)品特性 This antibody was obtained from a rabbit immunized with purified, recombinant Mouse LDLR / LDL Receptor (rM LDLR / LDL Receptor, NP_034830.2, Met 1-Arg 790) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.

目標(biāo)詳細情況

圖像 貯存及處理 使用細節(jié) 回頁首

目標(biāo)詳細情況

顯示 隱藏
別名 LDLR
背景 Low-density lipoprotein (LDL) is a type of lipoprotein that transports cholesterol and triglycerides from the liver to peripheral tissues, and enables fats and cholesterol to move within the water-based solution of the blood stream. The Low-Density Lipoprotein Receptor (LDLR) is the prototype member of the LDLR family of scavenger receptors which is involved in receptor-mediated endocytosis of specific ligands. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. LDLR recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles, as well as the apoE protein found in chylomicron remnants and VLDL remnants (IDL). After taken into the cell ending up in lysosomes, LDL is degraded and the cholesterol is made available for repression of microsomal enzyme HMG CoA reductase, the rate-limiting step in cholesterol synthesis. As a mosaic protein, the extracellular region of LDLR consists of seven N-terminal complement-like cysteinerich repeats followed by three EGF like repeats with a β-propeller YWTD containing motif, and a membrane proximal Ser/Thr rich region. Furthermore, it is reported that in case of HIV-1 infection, LDLR functions as a receptor for extracellular Tat (HIV-1 transactivator) into neurons, mediating its internalization in uninfected cells. Mutations in LDLR gene cause the autosomal dominant disorder, familial hypercholesterolemia.
NCBI Accession NP_034830.2

使用細節(jié)

圖像 貯存及處理 目標(biāo)詳細情況 回頁首

使用細節(jié)

顯示 隱藏
應(yīng)用備注 Concentration: 10 μl/Test, 0.1 mg/ml
限制 For Research Use only

貯存及處理

圖像 使用細節(jié) 目標(biāo)詳細情況 回頁首

貯存及處理

顯示 隱藏
狀態(tài) Liquid
緩沖液 Aqueous solution containing 0.5% BSA and 0.09% sodium azide
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事項 Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal
儲存條件 4 °C/-20 °C/-80 °C
儲存方法 This antibody is stable for 12 months from date of receipt when stored at 2 °C - 8 °C.
有效期 12 months

xy-6512R Alpha 1 microglobulinα1微球蛋白抗體
xy-4651R Alpha B Crystallinα晶狀體球蛋白B/αB-crystallin抗體
xy-5900R ADORA2B腺苷A2b受體/神經(jīng)生長因子1受體抗體
xy-6251R ARK5AMPK的相關(guān)蛋白激酶5抗體
xy-5927R ANP32C致瘤磷蛋白32相關(guān)蛋白1抗體
xy-6654R Adenosine deaminase腺苷脫氨酶抗體
xy-9130R ASB4含錨蛋白重復(fù)序列-細胞因子信號抑制物盒蛋白家族4抗體
xy-11504R ATRNL1ATRNL1蛋白抗體
xy-10081R AFP4aAFP4a蛋白抗體
xy-11627R APBB2鐵蛋白Fe65樣蛋白1抗體
xy-11637R APBB3鐵蛋白Fe65樣蛋白2抗體
xy-11639R APPBP2β淀粉樣蛋白前體蛋白結(jié)合蛋白2抗體
xy-11640R Aph-1b早老素穩(wěn)定因子樣蛋白/γ分泌酶組件蛋白APH1抗體
xy-10133R phospho-AKT1 (Tyr474)磷酸化蛋白激酶AKT1抗體
xy-10134R phospho-AKT1 (Ser473 + Tyr474)磷酸化蛋白激酶AKT1抗體
xy-11866R ASH1LASH1L蛋白抗體
xy-12040R ADRA2Cα2C-AR腎上腺素能受體抗體
xy-12977R AZI1中心體蛋白AZI1抗體
xy-7857R ALPK3α蛋白激酶3抗體（心肌）
xy-7856R ALOXE3表皮型脂氧合酶3抗體（魚鱗病相關(guān)蛋白）
xy-7926R ANKRD28錨蛋白重復(fù)域28抗體
xy-7886R AFF4淋巴細胞相關(guān)AF4樣蛋白抗體
xy-7962R ANKRD12錨蛋白重復(fù)結(jié)構(gòu)域蛋白12抗體
xy-7963R ANKRD13A錨蛋白重復(fù)結(jié)構(gòu)域蛋白13A抗體
xy-7964R ANKRD9錨蛋白重復(fù)結(jié)構(gòu)域蛋白9抗體
xy-7966R ANKS1A錨蛋白重復(fù)及SAM結(jié)構(gòu)域蛋白1A抗體
xy-7965R APM2脂肪特定轉(zhuǎn)錄因子2抗體
xy-7967R APOL3載脂蛋白L3抗體
xy-7969R ARMC3 (Cancer/testis antigen 81)腫瘤/睪丸抗原81抗體
xy-7976R ATXN7L2共濟失調(diào)蛋白7樣2抗體