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抗原
EPH Receptor B3 (EPHB3)
別名 tck, MGC83457, EPHB3, ETK2, HEK2, TYRO6, AW456895, Cek10, Etk2, MDK5, Sek4, Tyro6, CEK10, EK10, ek3, ephb3, fc62d03, rtk3, wu:fc62d03, zek3
抗原表位
其他選擇 AA 1-537
N-Term(16),AA 899-997 (8),AA 39-212 (7),AA 1-537 (5),AA 585-998 (4),C-Term (4),AA 1-998 (2),AA 29-59 (2),AA 204-225 (1),AA 30-554 (1),AA 38-550 (1),AA 607-998 (1),Extracellular Domain (1)
適用
其他選擇 Murine
Human(73),Murine (28),Rat ((Rattus)) (15),Chicken (13),Bovine (13),Dog (Canine) (13),Pig (Porcine) (13)
宿主
其他選擇 Rabbit
Rabbit(51),Mouse (27),Goat (1),Sheep (1)
克隆類型 (克隆位點)
單克隆 (1)
標記
其他選擇 PE
PE(3),Biotin (2),FITC (2),HRP (2),APC (1),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Alkaline Phosphatase (AP) (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1)
應用范圍
其他選擇 Flow Cytometry (FACS)
Western Blotting (WB)(61),ELISA (39),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (23),Immunohistochemistry (IHC) (22),Flow Cytometry (FACS) (16),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Enzyme Immunoassay (EIA) (4),Immunoassay (IA) (2),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (2),Immunoprecipitation (IP) (2),Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
規(guī)格 50 tests
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EPHB3 抗體
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免疫原 Recombinant Mouse EphB3 / HEK2 protein
克隆位點 1
亞型 IgG
特異性 Mouse EphB3 / HEK2
產(chǎn)品特性 This antibody was obtained from a rabbit immunized with purified, recombinant Mouse EphB3 / HEK2 (rM EphB3 / HEK2, NP_034273.1, Met1-Thr537) and conjugated with PE under optimum conditions, the unreacted PE was removed.
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別名 EPHB3
背景 Ephrin type-B receptor 3, EPH-like kinase 2, Tyrosine-protein kinase TYRO6, EPHB3, ETK2, HEK2 and TYRO6, is a single-pass type I membrane protein which belongs to theprotein kinase superfamily, tyr protein kinase family, ephrin receptor subfamily. EPHB3 contains twofibronectin type-III domains, oneprotein kinase domain and oneSAM (sterile alpha motif) domain. EphB3 is initially expressed in the sclerotome, but later is expressed predominantly in the dermatome. It is prominent expression is also detected in the developing heart, liver, posterior ventral limb bud mesenchyme, pharyngeal arches, and head mesenchyme. The EphB3 receptors are expressed during embryonic development in multiple regions of the central nervous system. The spatial profile of EphB3 receptors is co- localized to regions of the brain that had a high level of EphB3 receptor binding ligands. Its expression pattern suggests that EphB3 may play a role in the maintenance of mature neuronal connections or re-arrangement of synaptic connections during late stages of development. EphB3-ephrin-B interaction promotes MET by re-establishing epithelial cell- cell junctions and such an MET-promoting effect contributes to EphB3-mediated tumor suppression.
NCBI Accession NP_034273.1
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應用備注 Concentration: 10 μl/Test, 0.1 mg/ml
限制 For Research Use only
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狀態(tài) Liquid
緩沖液 Aqueous solution containing 0.5% BSA and 0.09% sodium azide
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事項 Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal
儲存條件 4 °C/-20 °C/-80 °C
儲存方法 This antibody is stable for 12 months from date of receipt when stored at 2 °C - 8 °C.
有效期 12 monthsxy-9304R ARL8BADP核糖基化樣因子8B抗體
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