CD244抗體 返回列表頁

CD244抗體

抗原
CD244 Molecule, Natural Killer Cell Receptor 2B4 (CD244)
別名 CD244, 2B4, NAIL, NKR2B4, Nmrk, SLAMF4, C9.1, F730046O15Rik, Ly90
抗原表位
其他選擇 AA 1-221
pTyr271(13),C-Term (12),AA 1-221 (7),Extracellular Domain (5),Internal Region (3),AA 1-365 (1),AA 20-221 (1),AA 22-221 (1)
適用
其他選擇 Human
Human(95),Murine (43),Rat ((Rattus)) (22),Pig (Porcine) (12),Rabbit (1)
宿主
其他選擇 Rabbit
Rabbit(50),Mouse (38),Rat (19),Goat (10)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
PE(14),FITC (12),Biotin (10),Alexa Fluor 647 (4),Alexa Fluor 350 (2),Alexa Fluor 488 (2),Alexa Fluor 555 (2),CF (2),Cy3 (2),Cy5 (2),Cy5.5 (2),Cy7 (2),HRP (2)
zui低檢測濃度 0.00245 ng/well
應(yīng)用范圍
其他選擇 ELISA
Flow Cytometry (FACS)(70),Western Blotting (WB) (41),ELISA (22),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (20),Immunoprecipitation (IP) (15),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9),Immunohistochemistry (IHC) (6),Functional Studies (Func) (3),Enzyme Immunoassay (EIA) (2),Immunofluorescence (IF) (2),Immunoassay (IA) (1),Immunocytochemistry (ICC) (1),Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
[Pubmed] 1 reference available
規(guī)格 100 μg
發(fā)貨至 中國 (更改)

CD244抗體

產(chǎn)品細(xì)節(jié)

引用 貯存及處理 使用細(xì)節(jié) 目標(biāo)詳細(xì)情況 回頁首

產(chǎn)品細(xì)節(jié)

顯示 隱藏
亞型 IgG
特異性 Human 2B4 / SLAMF4 / CD244
產(chǎn)品特性 Produced in rabbits immunized with purified, recombinant Human 2B4 (rh 2B4, NP_057466.1, Met 1-Arg 221). Total IgG was purified by Protein A affinity chromatography .
純化方法 Affinity Purified
過濾 0.2 μm filtered

目標(biāo)詳細(xì)情況

引用 貯存及處理 使用細(xì)節(jié) 回頁首

目標(biāo)詳細(xì)情況

顯示 隱藏
別名 CD244
背景 The CD244 antigen, also known as 2B4, is a cell surface glycoprotein implicated in the regulation of natural killer and T lymphocyte function. 2B4 is a member of the signaling lymphocyte activation molecule (SLAM)-related receptor family and is important for stimulating NK cell cytotoxicity and cytokine production, which is expressed on all NK cells, a subpopulation of T cells, monocytes and basophils. The 2B4 antigen identified on NK cells and T cells is capable of transmitting stimulatory signals and non-MHC-restricted killing. Reported as an activating receptor, human 2B4 can effectively activate and enhance NK cell-mediated cytotoxicity, induce secretion of IFN-γ and matrix metalloproteinases (MMPs), as well as NK cell invasiveness. As a cell surface glycoprotein of the Ig-superfamily structurally related to CD2-like molecules such as CD2, CD48, CD58, CD84, Ly-9, and SLAM, 2B4 (CD244) is expressed on all human NK cells, a subpopulation of T cells, basophils and monocytes. 2B4 activates NK cell mediated cytotoxicity, induces secretion of IFN-gamma and matrix metalloproteinases, and NK cell invasiveness.
NCBI Accession NP_057466.1
研究領(lǐng)域 Stem Cells, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells

使用細(xì)節(jié)

引用 貯存及處理 目標(biāo)詳細(xì)情況 回頁首

使用細(xì)節(jié)

顯示 隱藏
應(yīng)用備注 ELISA ELISA: 0.5-1 μg/mL This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human 2B4. The detection limit for Human 2B4 is 0.00245 ng/well.
限制 For Research Use only

貯存及處理

引用 使用細(xì)節(jié) 目標(biāo)詳細(xì)情況 回頁首

貯存及處理

顯示 隱藏
緩沖液 PBS with 5% trehalose
儲存液 Without preservative
注意事項 Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
儲存條件 4 °C/-20 °C/-80 °C
儲存方法 This antibody can be stored at 2 °C-8 °C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 °C to -70 °C.
有效期 12 months

xy-5208R phospho-ATG4C(Ser166)磷酸化自噬相關(guān)蛋白4C抗體
xy-5206R phospho-ATG16A(Ser213)磷酸化自噬相關(guān)蛋白16A抗體
xy-5209R phospho-AKT3 (Ser472)磷酸化蛋白激酶AKT3抗體
xy-5211R phospho-ADRB2 (Ser261)磷酸化腎上腺素能受體β2抗體
xy-5214R phospho-AQP2(Ser261)磷酸化水通道蛋白2抗體
xy-5204R phospho-ATG3 (Tyr18)磷酸化自噬相關(guān)蛋白3抗體
xy-4026R ALDOB醛縮酶2抗體
xy-3975R AMY2A胰腺α淀粉酶抗體
xy-7961R ANKRD11錨蛋白重復(fù)結(jié)構(gòu)域蛋白11抗體
xy-8440R phospho-c-ABL1+2 (Tyr393+429)磷酸化非受體酪氨酸激酶c-Abl抗體
xy-8449R phospho-ATF2 (Thr53)磷酸化活化復(fù)制因子2抗體
xy-5026R AKR1D1醛固酮還原酶家族1成員D1抗體
xy-5027R ARP4肝血管生成素相關(guān)蛋白抗體
xy-5028R ABHD5自水解酶結(jié)構(gòu)域5蛋白抗體
xy-5031R ACOT8?；o酶A硫酯酶8
xy-5032R Agpat2溶血磷脂酸?；D(zhuǎn)移酶β抗體
xy-10084R AFP4bAFP4b蛋白抗體
xy-5036R APOC2載脂蛋白C2抗體
xy-5035R Apolipoprotein A V載脂蛋白A5抗體
xy-5034R APOA2載脂蛋白A2抗體
xy-5033R AGPAT4溶血磷脂酸酰基轉(zhuǎn)移酶D抗體
xy-5039R APOE3載脂蛋白E3抗體
xy-5985R ABI3ABI基因家族2抗體
xy-5983R AARE氧化蛋白質(zhì)水解酶
xy-2390R Aconitase 2鐵調(diào)節(jié)蛋白2抗體
xy-5106R ALDH1乙醛脫氫酶1型抗體
xy-10082R AFP4aAFP4a蛋白抗體
xy-9296R ARHGAP32Rho GTP酶激活蛋白32抗體
xy-9886R Adropin能量平衡相關(guān)蛋白抗體
xy-4696R AEV polyprotein禽腦脊髓炎病毒AEV抗體