SERPINA5抗體 返回列表頁

SERPINA5抗體

抗原
serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 5 (SERPINA5)
別名 4933415L04, PAI-3, Pci, PAI3, PCI, PCI-B, PLANH3, PROCI
抗原表位
其他選擇 AA 1-406
AA 1-406(9),AA 4-33 (8),N-Term (7),C-Term (5),Internal Region (3),AA 17-406 (2),AA 1-181 (1),AA 190-406 (1),AA 20-406 (1),AA 25-449 (1),AA 260-309 (1)
適用
其他選擇 Human
Human(84),Murine (16),Dog (Canine) (15),Bovine (14),Rat ((Rattus)) (13),Chicken (12),Mammalian (1),Pig (Porcine) (1)
宿主
其他選擇 Mouse
Rabbit(52),Mouse (26),Goat (7),Rat (1)
克隆類型 (克隆位點)
單克隆 (4H10A7G6C1)
標(biāo)記
其他選擇 非結(jié)合性
HRP(4),Biotin (2),FITC (2),APC (1),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Alkaline Phosphatase (AP) (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),PE (1)
zui低檢測濃度 2.5 ng/well
應(yīng)用范圍
其他選擇 ELISA
Western Blotting (WB)(59),ELISA (28),Immunofluorescence (IF) (16),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Flow Cytometry (FACS) (6),Immunocytochemistry (ICC) (6),Immunohistochemistry (IHC) (5),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5),Immunoassay (IA) (4),Enzyme Immunoassay (EIA) (3),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (1),Neutralization (Neut) (1)
[Pubmed] 5 references available
規(guī)格 50 μg
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SERPINA5抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

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克隆位點 4H10A7G6C1
亞型 IgG1
特異性 Human SerpinA5 / Protein C inhibitor
產(chǎn)品特性 This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant human SerpinA5 (rhSerpinA5, aa 1-406, NP_000615.3). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
純化方法 Affinity Purified
過濾 0.2 μm filtered

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 SERPINA5
背景 Serpin A5, also well known as protein C inhibitor (PCI), is a member of the human serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent inhibitor of the protein C anticoagulant pathway at the levels of both zymogen activation and enzyme inhibition, serpinA5 additionally inhibits a variety of serine protease including thrombin, factor Xa, several kallekreins and acrosin, and plays a role in the processes of blood coagulation and fertilization. Serpin A5 also inhibits urinary plasminogen activator (uPA), a mediator of tumor cell invasion, and regulates tumor growth and metastasis by inhibiting angiogenesis. Furthermore, recent studies have identified PCI as a potent and direct inhibitor of activated HGFA (hepatocyte growth factor activator), suggesting a novel function in the regulation of tissue repair and regeneration. Similar to serpins C1 and D1, the thrombin inhibitory activity of serpinA5 is enhanced by heparin.
NCBI Accession NP_000615.3

使用細(xì)節(jié)

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使用細(xì)節(jié)

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應(yīng)用備注 ELISA ELISA: 0.5-1.0 μg/mL This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Human SerpinA5. The detection limit for Human SerpinA5 is 2.5 ng/well.
限制 For Research Use only

貯存及處理

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貯存及處理

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緩沖液 PBS with 5% trehalose
儲存液 Without preservative
注意事項 Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
儲存條件 4 °C/-20 °C/-80 °C
儲存方法 This antibody can be stored at 2 °C-8 °C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 °C to -70 °C.
有效期 12 months

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